Ilyang Xenta Duo Tablet 2.5/500 mg

Adult dose

This medication is administered 2 times a day with meals. 1. For patients not previously treated with metformin: The initial dosage is 1 tablet (1.25 mg/500 mg) taken twice daily, with an increase to a maximum of 2 tablets (2.5 mg/1000 mg) taken twice daily. 2. For transitioning from a combined therapy of linagliptin and metformin: Take the same dosage as previously administered initially. 3. For patients who are not achieving adequate blood glucose control with insulin and metformin therapy:

This medication can cause serious side effects such as lactic acidosis, so caution is needed. Lactic acidosis is a condition in which lactic acid builds up excessively in the body, making it acidic, and if untreated, it can lead to death. This medication should not be administered to individuals with allergies to its active or inactive ingredients, or to patients with type 1 diabetes, lactic acidosis, or diabetic ketoacidosis. It is also contraindicated in patients with significantly reduced kidney function, or in those with acute conditions that can affect kidney function such as acute myocardial infarction, severe infections, or dehydration. Patients with liver dysfunction or those with heart failure and pulmonary dysfunction should use this medication with caution. It should not be used by pregnant or breastfeeding women, and it is advisable to avoid it if planning to become pregnant. When using this medication, be cautious of symptoms of hypoglycemia, particularly when taken with sulfonylureas or insulin, as the risk of hypoglycemia is increased. If symptoms suspected of lactic acidosis such as abdominal pain, muscle pain, or lethargy occur, consult a doctor immediately. Regularly check kidney function, and discontinue or adjust dosage if abnormalities are found. If iodinated contrast agents need to be used for radiologic examinations, discontinue this medication for a certain period before and after the test and confirm kidney function. If surgery is planned, discontinue this medication 48 hours prior to surgery and only resume after normal kidney function is restored post-surgery. This medication can decrease vitamin B12 levels, so periodic monitoring for vitamin B12 deficiency is necessary during long-term use. This medication may interact with other drugs, so inform your doctor or pharmacist about any other medications you are taking. Elderly individuals commonly experience reduced kidney function, so dosage adjustment and regular kidney function checks are necessary. It is not recommended for children and pediatric patients under 10 years of age as safety and efficacy have not been established. In cases of overdose, there is a risk of lactic acidosis; hence, if suspected, seek proper treatment at a hospital immediately. Store this medication out of reach of children, avoid moisture, and do not transfer it to other containers.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, liver dysfunction (abnormal liver function tests, hepatitis), acute pancreatitis, angioedema, severe and disabling arthralgia, acute kidney injury, angina, acute myocardial infarction, unstable angina, cardiac arrest, congestive heart failure, diabetic foot, acute cholecystitis, acute cholecystitis, cholangitis, cholelithiasis, pneumonia, asthma, pulmonary dysfunction, respiratory

Mild side effects

Rhinitis, hypersensitivity, decrease and deficiency of vitamin B12, hypoglycemia (when used with sulfonylureas), taste disturbances, cough, decreased appetite, diarrhea, constipation (when used with insulin), nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe and disabling arthralgia, rhabdomyolysis, increased lipase, increased amylase, angioedema, dyspepsia, upper abdominal pain, stomatitis,

Store this medication in a tightly closed container to avoid exposure to air or moisture. Additionally, it is important to store it at room temperature between 1 degree Celsius and 30 degrees Celsius to maintain its effectiveness.

Appearance

Bright yellow, bilaterally convex oval shaped film-coated tablet

Package unit

30 tablets/box [6 tablets/PTP x 5 units]