Olmesartan Medoxomil and Amlodipine Tablets 5/40 mg

Adult dose

This medication is administered once daily, taking one tablet with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosages are as follows: - 5/20 mg: Given to patients whose blood pressure is not adequately controlled with monotherapy of Amlodipine 5 mg or Olmesartan Medoxomil 20 mg. - 10/20 mg: Given to patients whose blood pressure is not adequately controlled with monotherapy of Olmesartan Medoxomil 20 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be discontinued immediately upon confirmation of pregnancy. Individuals who are allergic to this medication's active ingredients or similar components, who are pregnant or breastfeeding, those with severe liver dysfunction, severe aortic valve stenosis, bile duct obstruction, patients undergoing dialysis, those in a state of shock, and specific diabetes patients should not take this medication. Patients with low blood pressure or those with conditions that cause blood vessels to dilate, patients with severe obstructive coronary artery disease, congestive heart failure, impaired kidney function, and those with liver dysfunction should use this medication cautiously and consult healthcare professionals immediately if symptoms of low blood pressure or other side effects occur. This medication can cause various side effects such as dizziness, headache, low blood pressure, orthostatic hypotension, heart palpitations, dyspepsia, nausea, skin rash, and edema, so any abnormal symptoms should be reported to healthcare providers. The use of this medication is prohibited during pregnancy due to the risk of fetal damage, and it should be replaced with safer alternatives if planning to conceive or if pregnancy is suspected. If breastfeeding, it is recommended to discontinue either breastfeeding or the medication, as this drug can be transmitted through breast milk and may affect the infant. It is advised not to use in children under 18 years, as safety and efficacy have not been established for this group. Elderly patients should start with a low dose due to the potential for increased drug concentrations in the body from decreased kidney and liver function and should adjust the dose cautiously. In case of overdose, symptoms of low blood pressure and reduced heart function may arise; appropriate treatment must be sought immediately. Avoid taking this medication with grapefruit juice, as it may excessively enhance the blood pressure-lowering effect, and consult healthcare providers regarding potential interactions when taking with other medications. Store this medication in a place out of reach of children, keeping it away from moisture, heat, and direct sunlight.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, severe skin reactions, jaundice, liver dysfunction, severe edema, markedly decreased urine output, severe neurological symptoms (dizziness, fainting), acute renal failure, increased blood creatinine, angioedema, autoimmune hepatitis, hives, leukopenia, thrombocytopenia, toxic epidermal necrolysis, sudden cardiac death, exacerbation of cerebral infarction, gum bleeding, acute renal failure.

Mild side effects

• Dizziness
• headache
• drowsiness
• decreased libido
• heart palpitations
• low blood pressure
• orthostatic hypotension
• cough
• nausea
• vomiting

This medication may be sensitive to air and moisture, and should be stored in a tightly closed container. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps to preserve the effectiveness of the medication for a longer period.

Appearance

Pale yellow round film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP × 2]