Medication info
Rivastatin 2 mg (Pitavastatin Calcium Hydrate)

Rivastatin 2 mg (Pitavastatin Calcium Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Pitavastatin Calcium Hydrate›200mg / 1 tablet
Manufacturer / importer
주식회사케이에스제약
Appearance
Very pale yellowish-red round film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202002753 · Approved 2020.04.20 · Insurance code 059000670

Summary

Main use
Improvement of hypercholesterolemia and dyslipidemia
Who takes it
Adults
Adult dose
For adults, the usual initial dose of pitavastatin calcium is 1 to 2 mg once daily. If the reduction effect on LDL cholesterol is not sufficient, the dose can be increased to a maximum of 4 mg per day. The dosage should be adjusted appropriately every 4 weeks or more, depending on the levels of LDL cholesterol, treatment goals, and patient response. The treatment effect of this drug is maintained with continuous administration.

Ingredients

Manufacturer
주식회사케이에스제약

Efficacy & effects

Improvement of hypercholesterolemia and dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
View approved original text

This medication helps lower total cholesterol, LDL cholesterol, Apo-B protein, and triglyceride levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It also increases HDL cholesterol levels, positively impacting cardiovascular health. It is effective in improving dyslipidemia when used in conjunction with dietary modifications. This medication is used to treat familial and non-familial hypercholesterolemia and dyslipidemia as classified by Fredrickson.

How to take

Adult dose

For adults, the usual initial dose of pitavastatin calcium is 1 to 2 mg once daily. If the reduction effect on LDL cholesterol is not sufficient, the dose can be increased to a maximum of 4 mg per day. The dosage should be adjusted appropriately every 4 weeks or more, depending on the levels of LDL cholesterol, treatment goals, and patient response. The treatment effect of this drug is maintained with continuous administration.

Precautions

This medication should not be used in certain patients. For example, patients who have an allergy to this drug, those with active liver disease or persistently elevated liver enzyme levels of unknown cause, patients with severe liver impairment or biliary obstruction, and patients taking cyclosporine should avoid this medication. Furthermore, women who have myopathy or are pregnant or may become pregnant, nursing mothers, and children are advised against using this medication. This product contains lactose, and individuals with lactose intolerance or certain genetic conditions should also avoid it. Patients with impaired kidney function or a history of liver impairment should use this medication cautiously. Co-administration with fibrates or niacin may cause muscle damage and worsening kidney function, so avoiding these combinations is advisable. People who consume large amounts of alcohol, those with hypothyroidism, elderly individuals, and those with muscle weakness should also exercise caution. During treatment with this medication, side effects such as muscle pain, weakness, abdominal pain, rash, and itching may occur. Symptoms of liver dysfunction, blood abnormalities, and decreased kidney function may also arise, necessitating regular testing. If muscle pain or tenderness becomes severe, discontinue use immediately and consult a physician. This drug is used for treating hypercholesterolemia, and accurate diagnosis, dietary adjustments, and exercise therapy should be undertaken beforehand. Regular testing of blood lipid levels during treatment is essential to confirm its effectiveness, as is periodic liver function testing. This drug can interact with specific medications, so caution is warranted when taken with cyclosporine, fibrates, niacin, erythromycin, etc. Taking these medications together may significantly increase the risk of muscle damage and worsening kidney function, therefore consulting with a physician or pharmacist is advised. Elderly patients are at higher risk for side effects due to decreased bodily functions and should take caution while using it. Pregnant or nursing individuals should not take this medication, and women of childbearing potential should discontinue immediately upon confirmation of pregnancy. The safety for children has not been established, so it's best not to use it. Lastly, this medication should be stored out of the reach of children and kept in its original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion, visual disturbances, paralysis, reduced urine output.

Mild side effects

  • Abdominal pain
  • rash
  • fatigue
  • numbness
  • itching
  • muscle pain
  • weakness
  • stiffness
  • drowsiness
  • insomnia
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  • headache
  • heaviness in the head
  • dizziness
  • dry mouth
  • dyspepsia
  • abdominal bloating
  • constipation
  • stomatitis
  • vomiting
  • loss of appetite
  • glossitis
  • nausea
  • gastrointestinal discomfort
  • diarrhea
  • thrombocytopenia
  • granulocytopenia
  • leukopenia
  • eosinophilia
  • leukocytosis
  • elevated globulin
  • Coombs test positive
  • anemia
  • increased urination
  • elevated BUN
  • elevated serum creatinine
  • aldosteronemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that blocks light, and the storage temperature should be maintained at room temperature between 1 degree and 30 degrees. Proper storage helps maintain the medication's effectiveness and prevents deterioration.

Appearance and packaging

Appearance

Very pale yellowish-red round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.