Medication info
Lometan HCT Tablet 5/40/12.5 Milligrams

Lometan HCT Tablet 5/40/12.5 Milligrams

Prescription medicationTablet경구
Ingredient · strength
Olmesartan Medoxomil›40mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)제뉴파마
Appearance
Pale yellow round film-coated tablets
Packaging
30 tablets/Alu-Alu[(10 tablets/Alu-Alu × 3)]
Approval status
Active

MFDS item code 202002697 · Approved 2020.04.17 · Insurance code 698004590

Summary

Main use
Improvement in blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
This medication is taken once daily with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows. - 5/20/12.5mg: Administered for patients whose blood pressure is not adequately controlled with amlodipine/olmesartan medoxomil 5/20mg combination therapy. - 5/40/12.5mg: Administered for patients whose blood pressure is not adequately controlled with amlodipine/olmesartan medoxomil 5/40mg combination therapy.
Child dose
Safety and efficacy in pediatric patients under 18 years have not been established; therefore, the administration of this medication is not recommended.

Ingredients

Manufacturer
(주)제뉴파마

Efficacy & effects

Improvement in blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension who have difficulty controlling blood pressure with existing treatments, through the combined therapy of amlodipine and olmesartan medoxomil. It effectively lowers blood pressure, reduces the risk of cardiovascular complications, and helps improve blood flow by dilating blood vessels. This allows for stable management of hypertension and maintenance of healthy blood pressure.

How to take

Adult dose

This medication is taken once daily with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows. - 5/20/12.5mg: Administered for patients whose blood pressure is not adequately controlled with amlodipine/olmesartan medoxomil 5/20mg combination therapy. - 5/40/12.5mg: Administered for patients whose blood pressure is not adequately controlled with amlodipine/olmesartan medoxomil 5/40mg combination therapy.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established; therefore, the administration of this medication is not recommended.

Precautions

This medication may cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy. Therefore, it should be stopped immediately upon confirmation of pregnancy. Patients with an allergy to this medication or its ingredients, those with certain heart, kidney, or liver diseases, pregnant or breastfeeding women, and patients with severe hypotension should not use this medication. Patients with depleted blood volume or sodium may experience symptoms of hypotension at the beginning of treatment, so careful monitoring of their condition is required, and appropriate measures should be taken if symptoms occur. Patients with impaired kidney function or kidney transplant recipients should have their kidney function monitored regularly through blood tests while taking this medication, as changes in kidney function may occur. This medication can also affect patients with impaired liver function, requiring dosage adjustments, and is not recommended for patients with severe liver impairment. Patients with heart valve disease or certain heart conditions, patients with primary aldosteronism, and patients with systemic lupus erythematosus should use this medication with caution. The hydrochlorothiazide component may cause acute angle-closure glaucoma or acute myopia; therefore, if sudden ocular pain or vision changes occur, immediate consultation with a healthcare provider is necessary. This medication may cause dizziness or lightheadedness due to its blood pressure-lowering effect, so caution is advised when driving or operating dangerous machinery. Additionally, while taking this medication, the skin may become sensitive to sunlight, so using sunscreen outdoors and avoiding sun exposure is recommended. There may be interactions with other drugs, so please inform your healthcare provider of any other medications you are taking, especially lithium, non-steroidal anti-inflammatory drugs, and other antihypertensives. In case of overdose, symptoms such as hypotension, palpitations, and bradycardia may appear, necessitating immediate medical attention. Finally, the safety of this medication in children has not been established, and elderly patients are recommended to start at low doses considering renal and liver function.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, breathing difficulties, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, cough with fever accompanying respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

  • Peripheral edema
  • headache
  • dizziness
  • upper respiratory tract infection
  • nasopharyngitis
  • urinary tract infection
  • sialadenitis
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
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  • neutropenia/agranulocytosis
  • hemolytic anemia
  • aplastic anemia
  • drug hypersensitivity
  • hyperkalemia
  • hypokalemia
  • loss of appetite
  • diabetes
  • hypercalcemia
  • hyperglycemia
  • hypomagnesemia
  • hyponatremia
  • hypochloremia
  • hypertriglyceridemia
  • hypercholesterolemia
  • hyperuricemia
  • hypochloremic metabolic alkalosis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, at a temperature between 1 and 30 degrees Celsius. Proper storage can help maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

Pale yellow round film-coated tablets

Package unit

30 tablets/Alu-Alu[(10 tablets/Alu-Alu × 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.