Samsung Dobesilate (Dihydrate of Calcium Dobesilate)

Adult dose

Adults: Administer the following doses of calcium dobesilate orally. 1. Vascular damage and retinopathy: 500-1000mg daily 2. Venous disease: Administer 750mg daily for 1-3 weeks, then 500mg daily. Take after meals with plenty of fluid. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in patients who are allergic to this drug or any of its components. This medication contains lactose, hence it should not be administered to patients with genetic lactose intolerance. Caution is advised when using this drug in patients with impaired kidney function, as its excretion may be difficult, and dosage reduction may be necessary, especially in patients with severe kidney disease requiring dialysis. This drug should also be used with caution in patients with impaired liver function, and the benefits of treatment should be reassessed if liver enzymes are elevated. It contains sulfites which may trigger allergic reactions, and patients with asthma may experience more frequent occurrences. Headache, abdominal pain, nausea, diarrhea, vomiting, arthralgia, and myalgia may occur during administration, and these symptoms generally resolve upon discontinuation of the medication. If hypersensitivity reactions such as skin rashes, itching, urticaria, or facial swelling occur, the medication should be discontinued immediately. Very rarely, serious side effects such as decreased blood cell counts may occur; hence, immediate consultation with a physician is required if fever or signs of infection appear. In the case of severe allergic reactions, the medication should be stopped immediately and medical assistance sought. The effects of this medication on driving or operating machinery are not known, thus caution is advised. Use during pregnancy is limited, and it is preferable to avoid it if possible. Since this medication is minimally excreted into breast milk, it is recommended to discontinue administration or breastfeeding. Safety in children has not been sufficiently studied; thus, caution is advised when used in this population. There are no special precautions for elderly patients, but general health status should be considered when using it. This medication may affect certain blood test results, so it is recommended to inform the physician before undergoing tests.

• Agranulocytosis
• neutropenia
• leukopenia
• skin rash
• allergic dermatitis
• itching
• urticaria
• facial edema
• anaphylactic reaction
• headache

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 degrees and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for an extended period.

Appearance

White rectangular tablet

Package unit

90 tablets/box [10 tablets/PTP × 9]