Medication info
Stoq 10 mg (Lafutidine)

Stoq 10 mg (Lafutidine)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Daewoong Bio Co., Ltd.
Appearance
White, round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202002641 · Approved 2020.04.14 · Insurance code 694002950

Summary

Main use
Gastrointestinal disorders (e.g., gastric ulcer and gastritis), pre-anesthetic medication, and combination therapy with antibiotics for Helicobacter pylori
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most patients healed within 8 weeks, although the healing period may vary in some patients. 2. Short-term treatment of duodenal ulcers The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most patients healed within 6 weeks, although the healing period may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis The usual dose is 10mg of lafutidine once daily, administered orally at bedtime. In clinical trials with treatment for up to 2 weeks, most patients healed within 2 weeks, although the healing period may vary in some patients. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori Administer 20mg of lafutidine, 500mg of clarithromycin, and 1000mg of amoxicillin twice daily for 7 days or 14 days. 5. Premedication before anesthesia The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis Administer 10mg of lafutidine per dose orally twice daily.

Ingredients

Manufacturer
Daewoong Bio Co., Ltd.

Efficacy & effects

Gastrointestinal disorders (e.g., gastric ulcer and gastritis), pre-anesthetic medication, and combination therapy with antibiotics for Helicobacter pylori

  • Gastric ulcer
  • duodenal ulcer
  • lesions of gastric mucosa due to acute gastritis
  • chronic gastritis
  • peptic ulcer
  • reflux esophagitis
View approved original text

This medication is used to treat gastric ulcers and duodenal ulcers, and to improve gastric mucosal damage caused by acute and chronic gastritis. Additionally, it is administered in conjunction with antibiotics to enhance effectiveness for patients with peptic ulcers associated with Helicobacter pylori infection. It also regulates gastric acid secretion when administered before anesthesia to prevent complications during surgery. It is utilized for the treatment of reflux esophagitis and improves the symptoms in patients. This medication is very useful for treating various gastrointestinal-related conditions.

How to take

Adult dose

1. Short-term treatment of gastric ulcers The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most patients healed within 8 weeks, although the healing period may vary in some patients. 2. Short-term treatment of duodenal ulcers The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most patients healed within 6 weeks, although the healing period may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis The usual dose is 10mg of lafutidine once daily, administered orally at bedtime. In clinical trials with treatment for up to 2 weeks, most patients healed within 2 weeks, although the healing period may vary in some patients. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori Administer 20mg of lafutidine, 500mg of clarithromycin, and 1000mg of amoxicillin twice daily for 7 days or 14 days. 5. Premedication before anesthesia The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis Administer 10mg of lafutidine per dose orally twice daily.

Precautions

This medication should not be used in patients with hypersensitivity to any component of this medication. Moreover, this medication contains lactose and should not be administered to patients with genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Caution should be taken when administering this medication to patients with a history of drug hypersensitivity, patients with poor liver function, patients with decreased kidney function, patients undergoing dialysis, and the elderly. This medication may rarely cause severe allergic reactions such as anaphylaxis, so if symptoms such as facial pallor, decreased blood pressure, generalized flushing, or difficulty breathing occur, administration should be stopped immediately and appropriate treatment should be received. Liver function abnormalities or jaundice may occur, so liver function tests should be conducted regularly, and if abnormalities are found, administration should be stopped. Blood disorders such as agranulocytosis or thrombocytopenia may occur, so if symptoms such as pharyngodynia, generalized malaise, or fever appear, the medication should be stopped immediately and a consultation with a physician is necessary. Additionally, rare abnormal reactions such as skin rash, seizures, interstitial nephritis, and heart block have been reported, so close observation is required in case of symptom development. Gastrointestinal symptoms may include constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite, while central nervous system symptoms may include headache, insomnia, drowsiness, and dizziness. Elderly patients may have decreased physical function, so careful adjustment of dosage and administration intervals should be observed, and their condition should be closely monitored. For patients undergoing dialysis, blood drug concentrations may increase, so administration should start carefully from a low dose. Pregnant women or women of childbearing potential should use it only when the therapeutic benefits outweigh the risks under a doctor's judgment, and it is advisable not to administer it to breastfeeding women as it may be excreted in breast milk. The safety for pediatric patients has not yet been established, so caution is needed for use. This medication should be kept out of reach of children and stored in its original container to prevent misuse or deterioration in quality. Finally, if malignancy is suspected, appropriate tests should be conducted for early diagnosis, and if confirmed as malignant gastric cancer, administration of this medication should be stopped.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • liver dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
Show 82 more
  • general malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell's syndrome
  • rhabdomyolysis
  • atrioventricular block
  • hypotonic contractions
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbances
  • dizziness
  • heat sensations
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • increased TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed maturation
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • fatigue
  • stomatitis
  • headache
  • chest pain
  • subdural hematoma
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • nasopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid artery stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • productive cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • cervical pain
  • itching
  • acne
  • contusion
  • insomnia
  • nonalcoholic fatty liver hepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be kept in a tightly sealed container. It is recommended to store the medication at room temperature between 1°C and 30°C, away from excessive heat or cold.

Appearance and packaging

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.