Medication info

OnePrep 1.38

Prescription medication경구
Ingredient · strength
Sodium Picosulfate Hydrate›10mg / 1 packetD-Sorbitol›37.9g / 1 packetAscorbic Acid›5g / 1 packet
Manufacturer / importer
(주)건강약품
Appearance
1) Preparation A: A white or pale yellow powder with a lemon scent 2) Preparation B: White or pale yellow crystals or crystalline powder
Packaging
Preparation A: 2 packets, Preparation B: 2 packets/box
Approval status
Active

MFDS item code 202002573 · Approved 2020.04.10

Summary

Main use
Bowel cleansing effect for colon examination preparation
Who takes it
Adults
Adult dose
Adults aged 19 to under 80 years should take this medication in two doses 4-5 hours before the colonoscopy. 1) Take 1 cup (230 mL) of the prepared solution over 10 minutes, then take 460 mL (230 mL * 2 cups) of water divided over approximately 20 minutes. 2) After completing the first dose, repeat step 1) again over approximately 30 minutes. If nausea or vomiting occurs, it may help to pause the intake for 20-30 minutes.

Ingredients

Manufacturer
(주)건강약품

Efficacy & effects

Bowel cleansing effect for colon examination preparation

View approved original text

This medication is used to clean the intestines before colon X-ray examinations or endoscopies. It aids in removing residual material from the colon as part of the preparation process for an accurate diagnosis during the examination. Therefore, it plays an important role in effective pre-treatment before the examination. This medication helps enhance the reliability of the examination results and facilitates a smooth examination.

How to take

Adult dose

Adults aged 19 to under 80 years should take this medication in two doses 4-5 hours before the colonoscopy. 1) Take 1 cup (230 mL) of the prepared solution over 10 minutes, then take 460 mL (230 mL * 2 cups) of water divided over approximately 20 minutes. 2) After completing the first dose, repeat step 1) again over approximately 30 minutes. If nausea or vomiting occurs, it may help to pause the intake for 20-30 minutes.

Precautions

This medication should not be used in patients with bowel obstruction, gastrointestinal blockage, perforation, toxic colitis, or toxic megacolon. It should be administered with caution, especially in severe ulcerative colitis patients. Individuals allergic to this medication or its components should not take it. Additionally, it should be avoided in cases of suspected gastrointestinal blockage or perforation, dehydration, or serious congestive heart failure. Patients with active malignancy or colon disorders that could cause serious mucosal damage, patients with gastric paralysis, and those with bowel obstruction should also refrain from using this medication. Patients with glucose-6-phosphate dehydrogenase deficiency, unconscious patients, children under the age of 19, unexplained abdominal pain patients, and those with hereditary fructose intolerance are also not suitable for this medication. Patients with gastrointestinal ulcers, nausea and vomiting, patients with acute abdominal conditions requiring surgery, patients with rhabdomyolysis, and those with active inflammatory bowel disease should not take this medication. Caution should be exercised when administering this medication to patients with intestinal strictures or severe constipation, elderly or frail patients, those with impaired vomiting reflexes or altered consciousness, patients with acute severe inflammatory diseases, and those with dysphagia. Patients experiencing significant abdominal bloating or pain, those with severe ulcerative colitis, patients with renal impairment or inflammatory bowel disease, and those taking medications that may affect fluid or electrolyte balance should also be monitored closely. This medication may cause gastrointestinal symptoms such as abdominal bloating, abdominal pain, discomfort, rectal discomfort, bloody stools, belching, nausea, vomiting, dizziness, headaches, sleep disturbances, thirst, chills, as well as signs of hepatic dysfunction and thirst. Before and during use, it is essential to monitor bowel movements carefully, as bowel activity typically begins within approximately 1 hour after taking the medication. If significant abdominal bloating or pain occurs, the speed of administration should be slowed or temporarily halted, and medical advice should be sought if necessary. If symptoms of fluid or electrolyte imbalance appear, condition should be confirmed through blood tests and appropriate treatment should be provided. Patients who are frail or have poor kidney function should have regular checks for electrolyte and kidney function. This medication can cause diarrhea, so adequate hydration is important. It is advisable to have a light meal before taking it and to finish eating at least 1 hour before taking the medication. Avoid solid foods just before taking this medicine. Non-absorbable sugars such as sorbitol in this medication can produce gas in the intestines, posing a risk of explosion when using an electric cautery. During colonoscopy, the risk can be reduced by using CO2 gas for insufflation. The effects of this medication on driving or operating machinery are not known, but caution is advised as dizziness may occur. Absorption of other oral medications taken within 1 hour before this drug may be inhibited, so it is advisable to consult a doctor or pharmacist when taking important medications. Women who are pregnant or may become pregnant, as well as nursing mothers, should use this medication only if the diagnostic benefits outweigh the risks, as its safety has not been established. Safety and efficacy have not been confirmed in pediatric patients, and caution is required in elderly patients as they may be more sensitive to medications. In case of overdose, there is a risk of dehydration, electrolyte abnormalities, or decreased blood volume, so immediate medical treatment should be sought if symptoms occur. This medication should not be mixed with other ingredients or flavors, and should be taken immediately after dissolving it in water. Any solution not used within 25 hours should be discarded. Store this medication out of the reach of children and do not transfer it to other containers for quality maintenance and safety.

Side effects and when to seek care immediately

Mild side effects

  • Abdominal bloating
  • abdominal pain
  • abdominal discomfort
  • rectal discomfort
  • bloody stools
  • belching
  • nausea
  • vomiting
  • dizziness
  • headaches
Show 17 more
  • sleep disturbances
  • thirst
  • chills
  • gastroesophageal reflux disease
  • chronic gastritis
  • intestinal metaplasia
  • anal fissures
  • erosive gastritis
  • fatty liver
  • runny nose
  • nasal congestion
  • reflux laryngitis
  • allergic rhinitis
  • Helicobacter infection
  • colon adenomas
  • colon neoplasms
  • injection site pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the effectiveness of the drug.

Appearance and packaging

Appearance

1) Preparation A: A white or pale yellow powder with a lemon scent 2) Preparation B: White or pale yellow crystals or crystalline powder

Package unit

Preparation A: 2 packets, Preparation B: 2 packets/box

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.