Medication info

Pazilect 0.5 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›0.78mg / 1 tablet
Manufacturer / importer
Daewoo Pharmaceutical Co., Ltd.
Appearance
White or almost white, flat round tablets with edges
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Expired

MFDS item code 202002509 · Approved 2020.04.09

This product's status changed to Expired on 2025.04.09. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If it is well tolerated and the clinical response is insufficient, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Daewoo Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor dyskinesia symptoms
View approved original text

This medication is used for patients with idiopathic Parkinson's disease and can be used as monotherapy or as an adjunct therapy with dopamine agonists, especially in the early stage. It also helps alleviate the symptoms associated with motor dyskinesia as an adjunct to levodopa therapy, thereby improving patients' motor function and quality of daily life.

How to take

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If it is well tolerated and the clinical response is insufficient, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used in patients allergic to the active ingredient or other components. It should be avoided if the patient is taking other MAO inhibitors or certain natural medicines, or if they have recently stopped taking them, as it can be dangerous to take them together. Particular caution is needed for patients taking medications such as pethidine, tramadol, or dextromethorphan due to the risk of serious side effects. It is safe not to administer this medication to patients with moderate to severe liver impairment. This medication can cause various side effects such as headaches, dizziness, nausea, and insomnia, so if symptoms are severe or persistent, consultation with a healthcare professional is necessary. Patients with Parkinson's disease may experience hallucinations, confusion, and dyskinesia symptoms, which should be reported immediately. Blood pressure elevation or hypotension may occur while taking this medication, so it is important to regularly monitor blood pressure status. When used with dopamine-related treatments, impulse control disorders, excessive drowsiness during the day, or sudden sleep can occur; therefore, caution is needed. Activities requiring concentration, such as driving or operating machinery, should only be performed after confirming that there are no symptoms of drowsiness or sleep after taking this medication. There are many drug interactions, so especially when used with antidepressants, sympathomimetics, or some antibiotics, it is essential to consult with a healthcare professional. Women who are pregnant or breastfeeding should take caution when using this drug, and safety has not been established in pediatric patients. Serious side effects may occur in case of overdose, so it is crucial to adhere to the prescribed dosage and administration, and seek immediate medical attention in case of overdose. This medication should be kept out of reach of children and stored at the appropriate temperature to maintain quality.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urinary urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • joint pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle hypertonicity
  • myasthenia
  • anorexia
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • hematoma
  • hemorrhage
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • melanoma
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive spending or purchasing
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • vertebral fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • hallucinations
  • semi-consciousness
  • gait disturbance
  • ocular motor seizures
  • facial paralysis
  • spinal stenosis
  • worsening of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • weakness of limbs
  • concussion
  • unspecified abrasion
  • laceration
  • scoliosis
  • thirst
  • hypoalbuminemia
  • electrolyte imbalance
  • hematuria
  • frequent urination
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin thickening
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • hypersecretion of mucus
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movement frequency
  • unspecified gastrointestinal disease
  • esophagitis
  • excess gastric acid
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • intestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delirium
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin paresthesia
  • tremor
  • freezing phenomenon
  • limb tremors
  • myoclonic tremors
  • leg cramps
  • polyuria
  • shaking
  • stuttering
  • speech impairment
  • vocal cord paralysis
  • language impairment
  • localized inflammation
  • pruritus
  • urticaria
  • eyelid skin disease
  • furuncle
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis
  • chest burning
  • general weakness
  • fatigue
  • aggravated tremors

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture, and the storage temperature should be a cool place between 1 and 25 degrees Celsius. It is important to store it safely, avoiding direct sunlight and high temperatures.

Appearance and packaging

Appearance

White or almost white, flat round tablets with edges

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.