Olmesartan Medoxomil 40mg Tablets

Adult dose

The recommended initial dose for adults is 10mg once daily, regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20mg once daily. If additional blood pressure reduction is required, it may be increased up to a maximum of 40mg once daily. The antihypertensive effect will be observed within 2 weeks of starting treatment, with maximum effect seen after about 8 weeks. If blood pressure control is not achieved with monotherapy, thiazide diuretics like hydrochlorothiazide may be combined for treatment. For adherence improvement, it is recommended to take the medication at the same time each day (e.g., in the morning). In patients at risk of intravascular volume depletion (e.g., patients on diuretics, particularly those with renal impairment), it is recommended to start treatment at a lower dose while monitoring their condition closely.

Child dose

Safety and efficacy in pediatric patients have not been established.

This drug can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to any of the ingredients in this medication, those who are pregnant or breastfeeding, patients undergoing renal dialysis, those with severe liver dysfunction, biliary obstruction, lactose intolerance, or certain diabetes types should not use this medication. Patients with decreased blood volume or sodium, impaired renal function, renovascular hypertension, at risk for hyperkalemia, or heart valve disease should use this medicine cautiously and closely monitor blood pressure and renal function. Dizziness may occur during use; therefore, it is recommended to avoid driving or operating hazardous machinery. Generally, this medication is well tolerated and has few side effects, but symptoms such as dizziness, headaches, dyspepsia, muscle pain, and rash may occur. Rarely, serious side effects such as angioedema, hyperkalemia, and renal failure may arise, so if any unusual symptoms occur, consult a physician immediately. If chronic diarrhea or weight loss persists, consideration should be given to stopping the medication, and any such symptoms should be reported to healthcare professionals immediately. Interactions may occur with other antihypertensive drugs, potassium-sparing diuretics, lithium, and non-steroidal anti-inflammatory drugs, so it is essential to consult with a doctor or pharmacist about other medications being taken. Taking this medication during pregnancy may cause serious issues such as hypotension, renal dysfunction, or malformations in the fetus. If planning pregnancy or discovering a pregnancy, it is crucial to stop taking the medication and consult a physician. If breastfeeding, this medication may be transmitted through breast milk, so a decision to continue breastfeeding or discontinue the medication should be discussed with a physician. Safety for pediatric use has not been established, so it should be used cautiously in children. Elderly patients may have increased drug concentrations in the body, requiring careful use. Overdosage may lead to hypotension or palpitations; if these symptoms occur, emergency treatment should be sought immediately. Although this medication has not been reported to be carcinogenic or genotoxic with long-term use, regular check-ups and adherence to healthcare provider instructions before and after use are necessary.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• chest pain
• vasogenic edema
• urticaria

Mild side effects

• Dizziness
• headache
• palpitations
• abdominal pain
• dyspepsia
• gastroenteritis
• nausea
• hypercholesterolemia
• hyperlipidemia
• hyperuricemia

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, while storing the medication, avoid places that are too hot or too cold; it is advisable to keep it at room temperature between 1°C and 25°C.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle