Seahrin Capsule 50 Milligrams (Diacerhein)

Adult dose

Adults: Administer diacerein 50∼100mg per day orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used by patients suffering from inflammatory bowel disease. For example, it should not be administered to patients with ulcerative colitis or Crohn's disease. Patients with bowel obstruction syndrome or those experiencing unexplained abdominal pain should also avoid taking this medication. Similarly, individuals allergic to this drug or its components, as well as those allergic to Rhein-class medications, should not use it. Patients with liver disease or a history of liver problems should avoid taking this medication, and it should not be used by children under 15 years of age. Since this medication contains lactose, it should not be administered to patients with genetic disorders that prevent lactose digestion. In patients with a history of small intestine or colon diseases, this medication must be used cautiously. Pregnant or breastfeeding women should also exercise caution when taking this medication. Elderly patients over 65 years should reduce the dosage, and those allergic to Yellow No. 5 should also be careful. This medication may cause gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain, and long-term use may increase the risk of gastrointestinal bleeding, ulcers, or perforation. If diarrhea worsens, dehydration or electrolyte imbalance may occur, so it is important to consult a doctor immediately if symptoms appear. Skin symptoms such as itching, rashes, and eczema may occur, and there is a possibility of liver dysfunction, so caution is necessary. Patients using this medication long-term must strictly follow medical advice, and if diarrhea occurs, they should discontinue use and seek medical attention. To prevent liver damage, it is advisable to limit alcohol intake, and should any liver dysfunction symptoms appear, immediate discontinuation of the medication is necessary. Taking antacids containing calcium, magnesium, or aluminum, or salt alongside this medication could hinder its absorption, so a minimum interval of 2 hours should be maintained. Using diuretics together may enhance the diuretic effect, posing risks of dehydration or hypokalemia, so caution is essential. When combined with cardiac glycosides, the risk of arrhythmias may increase, so it is crucial to consult a doctor. It is advisable for women who are pregnant or breastfeeding to avoid this medication as it may affect the fetus or newborn. In cases of overdose, severe diarrhea may occur, and electrolyte supplementation or other treatments may be necessary.

Diarrhea, loose stools, abdominal pain, gastrointestinal disturbances (hemorrhage, ulcers, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated liver enzymes in serum

This medication should be stored in a tightly sealed container to protect it from exposure to air or moisture, and it is advisable to keep it at room temperature between 1 and 30 degrees Celsius. Storing it this way allows the medication to maintain its efficacy for a longer period.

Appearance

A hard capsule with a yellow upper part and a light yellow lower part containing a brownish-yellow content.

Package unit

Bottle - 30 capsules/bottle, Bottle - 500 capsules/bottle