LinaMax Tablet 2.5/850 mg

Adult dose

The dosage of this medication is determined based on each patient’s treatment status, not exceeding the maximum recommended doses of 2.5 mg of linagliptin and 1000 mg of metformin taken twice daily. This medication is administered twice daily with meals. 1. In cases not previously treated with metformin: The initial dose is 1 tablet of this medication 2.5/500 mg twice daily, and the dose may be increased to 1 tablet of 2.5/1000 mg twice daily. 2. Metformin

This medication has been reported to cause serious side effects such as lactic acidosis, and caution should be taken. It is contraindicated for individuals with allergies to the active ingredients or components, type 1 diabetes patients, and those with severe renal impairment. Use of this medication should be avoided in cases of acute conditions that may affect kidney function, such as dehydration, severe infections, or acute heart failure. Patients with poor liver function or gastrointestinal disorders, those in acute alcohol intoxication, or with alcohol dependence should also avoid using this medication. Pregnant or nursing women are advised not to take this medication. This medication entails a risk of hypoglycemia, especially when used together with sulfonylureas or insulin, which may cause blood sugar levels to drop too low. Patients with diminished kidney function should have regular kidney function tests before taking this medication, and it should not be used if kidney function is severely impaired. Acute pancreatitis or skin blistering conditions may occur, thus any persistent severe abdominal pain or abnormal skin symptoms during usage should be consulted with a doctor immediately. This medication may lower vitamin B12 levels, therefore it is advisable to regularly check for vitamin B12 deficiency when taken for extended periods. There may be interactions when taken with other medications; hence, it is crucial to inform healthcare providers of all current medications. Elderly individuals often experience decreased kidney function, so renal function should be monitored frequently, and dosage adjustments made if necessary. If planning a pregnancy or if currently pregnant, this medication should be avoided, and alternative treatment methods for blood sugar control should be considered. Children and adolescents are not recommended to use this medication as its safety and efficacy have not been sufficiently established. In cases of overdose, gastrointestinal symptoms and lactic acidosis may occur, necessitating immediate hospital treatment. This medication should be stored away from moisture and kept out of reach of children, and it is advisable not to transfer to another container.

Serious side effects

• Urticaria
• angioedema
• lactic acidosis
• pancreatitis
• bullous pemphigoid
• severe allergic reactions
• severe skin adverse reactions
• respiratory distress
• liver dysfunction (jaundice)
• severe arthralgia

Mild side effects

• Nasopharyngitis
• hypersensitivity
• decreased and deficiency of vitamin B12
• hypoglycemia
• taste disorder
• cough
• decreased appetite
• diarrhea
• constipation
• nausea

This medication may be sensitive to air or moisture and should be stored in a tightly sealed container. Also, avoid very hot or very cold conditions, and store at room temperature between 1°C and 30°C.

Appearance

A bright orange oval film-coated tablet with both sides convex.

Package unit

For domestic use - 30 tablets/PTP [6 tablets/PTP x 5 pieces]