Gatidine 20 mg (Famotidine)

Adult dose

For gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: Administer 20 mg of Famotidine orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg once daily (at bedtime). In cases of upper gastrointestinal bleeding, switch from intravenous treatment to oral administration. For acute gastritis, acute exacerbation of chronic gastritis: Administer 10 mg of Famotidine orally twice daily (after breakfast, after dinner).

This medication should not be used by individuals who have had an allergic reaction to this medication or similar types of drugs. Additionally, this medication contains lactose, so individuals with a genetic issue that prevents lactose digestion should avoid taking it. Particular caution should be exercised when using this medication in individuals with a history of drug allergies, impaired kidney function, heart disease, liver dysfunction, and the elderly. In cases of reduced kidney function, the concentration of the medication may increase, requiring a decrease in dosage or an increase in dosing intervals. Individuals with heart disease may be at risk of side effects affecting the heart, necessitating caution. This medication may cause rare but serious side effects such as severe allergic reactions, blood-related disorders, serious abnormalities in the skin and mucous membranes, liver dysfunction, muscle damage, cardiac rhythm disturbances, consciousness disturbances, nephritis, and pneumonia; if any abnormal signs appear, discontinue use immediately and consult a doctor. Common side effects may include skin rash, decrease in blood cell count, digestive issues, blood pressure changes, respiratory issues, liver function abnormalities, neurological symptoms, endocrine abnormalities, and joint pain. The medication should be used at the minimum necessary dose while observing its effectiveness carefully, and if no effect is observed, alternative treatments should be considered. The medication dissolves in the mouth but is not absorbed sublingually, so it should be swallowed with water or saliva. Patients undergoing hemodialysis should be cautious when using this medication with specific phosphate binders as the effectiveness of the phosphate binders may be reduced. This medication may alter the drug concentration or effect when taken with certain antifungal agents or some chemotherapeutic drugs, so consultation with a doctor or pharmacist is essential. Elderly patients may be more likely to have impaired kidney function, potentially leading to prolonged retention of the drug in the body, thus necessitating dosage adjustment. Pregnant women or women who may become pregnant should only use this medication when the benefits of treatment outweigh the risks, as safety during pregnancy has not been fully confirmed. This medication can also be passed through breast milk, so it is advisable to discontinue breastfeeding while using this medication. Safety in children has not been fully confirmed, so caution is advised when using this medication in this population. Finally, this medication may obscure the symptoms of gastric cancer, so it should only be used after it has been confirmed that the condition is not gastric cancer.

Serious side effects

Shock, hypersensitivity (anaphylaxis, difficulty breathing, generalized flushing, angioedema (facial swelling, pharyngeal edema), urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia (including Torsades de Pointes), ventricular fibrillation, consciousness disturbances, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, and failure

Mild side effects

• Rash
• urticaria (redness)
• facial swelling
• decreased white blood cells
• increased eosinophils
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting

This medication should be stored in a tightly sealed container to protect it from air and moisture. The appropriate storage temperature is room temperature between 1°C and 30°C, and it is advisable to avoid extremely hot or cold places.

Appearance

Light green, round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle