Itaxraputidine Tablet

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine per dose, administered orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine per dose, administered orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine once daily, administered orally at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20 mg, clarithromycin 500 mg, and amoxicillin 1000 mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10 mg of lafutidine per dose orally twice daily.

This medication should not be administered to patients with hypersensitivity to any component of this product. Since it contains lactose, it should not be used by patients with lactose intolerance or certain genetic problems. Patients with a history of drug hypersensitivity, impaired liver or kidney function, those undergoing dialysis, and the elderly should be especially cautious when using this drug. This medication can cause serious allergic reactions; if any symptoms such as facial pallor, hypotension, or difficulty breathing occur during administration, treatment should be discontinued immediately and appropriate medical care should be sought. Regular liver function tests are necessary, as abnormalities such as liver dysfunction and jaundice may occur, and drinking should be discontinued if abnormalities are found. Agranulocytosis or thrombocytopenia may occur, so if symptoms such as sore throat, lethargy, or fever occur, it is necessary to consult a physician immediately. Rarely, serious side effects such as skin rashes, seizures, and heart block have been reported; if any unusual symptoms occur, immediate consultation with a healthcare professional is required. Gastrointestinal symptoms such as constipation, diarrhea, vomiting, abdominal distension, and loss of appetite may occur, and central nervous system symptoms such as headache, insomnia, and drowsiness have also been reported. Since it can affect liver and kidney functions, regular blood tests and kidney function tests are necessary. Pregnant women or women who may become pregnant should use it under a physician's supervision, and it is advisable for nursing mothers not to use this medication. Safety in pediatric patients has not been established, so it should be administered cautiously to children. The elderly should pay attention to dose adjustment and administration intervals due to decreased physical functions and closely observe their condition. Dialysis patients should start at a low dose and carefully administer it as blood concentration may increase. This medication must be kept out of reach of children and stored in its original container to maintain drug quality and prevent misuse. Symptoms of malignancy may be masked during the use of this drug, so in patients with gastric ulcers suspected of malignancy, appropriate testing should be conducted and treatment should be discontinued if necessary. If there is no therapeutic effect, it is advisable to switch to another treatment method, and blood, liver, and kidney functions should be regularly monitored for safe use.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly closed container to avoid contact with air or moisture. The appropriate storage temperature is between 1 and 30 degrees Celsius at room temperature, avoiding excessively hot or cold places.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle