Medication info

Mytorin Tablets 10/10 Milligrams

Prescription medicationTablet경구Expired
Ingredient · strength
Ezetimibe›10mg / 1 tabletSimvastatin›10mg / 1 tablet
Manufacturer / importer
아이큐어(주)
Appearance
White to pale yellow, bilaterally convex rectangular tablets
Packaging
For domestic use - 30 tablets/PTP [(10 tablets/PTPX3)]
Approval status
Expired

MFDS item code 202002326 · Approved 2020.04.02

This product's status changed to Expired on 2025.04.02. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of cholesterol and lipids in patients with hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia
Who takes it
Adults
Adult dose
This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg daily, with a standard initial dose typically recommended as 10/20mg daily. Patients who require less reduction in LDL cholesterol may start with 10/10mg once daily. After starting treatment or adjusting the dose, blood lipid levels should be checked at intervals of more than 4 weeks.

Ingredients

Manufacturer
아이큐어(주)

Efficacy & effects

Improvement of cholesterol and lipids in patients with hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed hyperlipidemia
  • homozygous familial hypercholesterolemia
  • atherosclerotic vascular disease due to hypercholesterolemia
  • dyslipidemia
View approved original text

This medication is used as an adjunct to dietary therapy in patients with primary hypercholesterolemia and mixed hyperlipidemia to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides, and to increase HDL cholesterol. Additionally, it may be administered to patients with homozygous familial hypercholesterolemia when other treatments are insufficient or in combination therapy. This medication should be used alongside an appropriate dietary regimen, taking into account the patient’s risk factors. It is important to check for other secondary causes and to combine treatments if necessary. Regular monitoring of lipid levels is vital to assess the effectiveness of treatment. This medication is used to improve lipid levels in blood for the treatment of hypercholesterolemia.

How to take

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg daily, with a standard initial dose typically recommended as 10/20mg daily. Patients who require less reduction in LDL cholesterol may start with 10/10mg once daily. After starting treatment or adjusting the dose, blood lipid levels should be checked at intervals of more than 4 weeks.

Precautions

This medication is used to lower cholesterol levels in the blood and helps to reduce the risk of cardiovascular disease. Serious muscle-related adverse reactions, such as myopathy or rhabdomyolysis, may occur when taking this medication, so caution is advised. If symptoms such as muscle pain or weakness appear, consult a physician immediately. Additionally, this medication may affect liver function, so patients with liver disease or abnormally high liver function test results should not take it. Women who are pregnant or breastfeeding should not take this medication, and women of childbearing age should only take it after confirming the possibility of pregnancy. The risk of myopathy may increase when this medication is taken with certain other drugs; therefore, it is essential to inform the doctor or pharmacist about any medications being taken. Elderly patients and those with chronic kidney disease require closer monitoring when taking this medication. During treatment, it is recommended to regularly check blood tests to monitor liver function and muscle condition. It is advisable to avoid certain foods or drinks, such as grapefruit juice, while taking this medication, and to seek immediate medical help in case of overdose. Lastly, if any new symptoms or adverse reactions arise during treatment with this medication, inform medical personnel immediately and seek consultation.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions
  • High fever accompanied by severe rash, blisters, skin shedding, pain in oral/ocular mucosa, severe skin adverse reactions
  • Shortness of breath or breathing difficulties, asthma attack, respiratory abnormalities with cough and fever
  • Yellowing of the skin or eyes (jaundice), severe lethargy, liver abnormalities (jaundice)
  • Sudden and severe headache

Mild side effects

  • Headache
  • diarrhea
  • influenza
  • upper respiratory tract infection
  • muscle pain
  • limb pain
  • fatigue
  • nausea
  • abdominal pain
  • constipation
Show 26 more
  • upper abdominal pain
  • vomiting
  • chest pain
  • chest discomfort
  • weakness
  • sensory impairment
  • cough
  • edema
  • thirst
  • facial swelling
  • fainting
  • insomnia
  • gastritis
  • atrophic gastritis
  • indigestion
  • mucous stools
  • irritable bowel syndrome
  • sore throat
  • alopecia
  • itching
  • gynecomastia
  • reduced libido
  • sexual dysfunction
  • anemia
  • weight loss
  • HbA1c and fasting

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. Additionally, it is important to store it at room temperature between 1 degree and 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

White to pale yellow, bilaterally convex rectangular tablets

Package unit

For domestic use - 30 tablets/PTP [(10 tablets/PTPX3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.