Medication info

Nobadin Tablets (Amlodipine Besylate)

Prescription medicationTablet경구Expired
Ingredient · strength
Amlodipine Besylate›6.944mg / 1 tablet
Manufacturer / importer
주식회사케이에스제약
Appearance
White octagonal tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Expired

MFDS item code 202002284 · Approved 2020.04.01

This product's status changed to Expired on 2025.04.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of myocardial ischemia due to hypertension and coronary artery disease (stable angina, variant angina) and reduction of the risk of hospitalization and vascular interventions.
Who takes it
Adults
Adult dose
Take 5 mg orally once daily as amlodipine. Depending on the patient's response, the dose may be increased to a maximum of 10 mg once daily.\nAdjust as appropriate according to age and symptoms.

Ingredients

Manufacturer
주식회사케이에스제약

Efficacy & effects

Improvement of myocardial ischemia due to hypertension and coronary artery disease (stable angina, variant angina) and reduction of the risk of hospitalization and vascular interventions.

  • Hypertension
  • fixed occlusion of the coronary artery
  • vascular spasm of the coronary vessels
  • vascular contraction
  • myocardial ischemia
View approved original text

This medication is used for the treatment of hypertension, stable angina, and myocardial ischemia caused by vascular spasm. Additionally, it reduces the risk of hospitalization due to angina in patients who have been diagnosed with coronary artery disease through recent angiography and who do not have heart failure and have a cardiac output of more than 40%. It also helps to reduce the risks associated with vascular interventions after coronary artery surgery. This medication is effective for the treatment and symptomatic improvement of cardiovascular diseases and plays an important role in maintaining patient health.

How to take

Adult dose

Take 5 mg orally once daily as amlodipine. Depending on the patient's response, the dose may be increased to a maximum of 10 mg once daily.\nAdjust as appropriate according to age and symptoms.

Precautions

This medication should not be used in certain patients.\nFor example, it should not be administered to patients with a history of allergy to this drug or similar drugs, nursing mothers, patients with severe liver dysfunction, severe aortic stenosis, and patients in shock.\nMoreover, it should be used cautiously in patients with severe hypotension, patients who require dialysis due to severely impaired kidney function, elderly patients, and women who are pregnant or may become pregnant.\nWhen using this medication, caution is needed as various side effects may occur.\nThe most common side effects include flushing of the face, fatigue, symptoms of swelling, a sensation of rapid heartbeat, dizziness, headache, drowsiness, abdominal pain, and nausea.\nRarely, it can cause severe hypotension, skin rash, itching, allergic reactions, cardiac arrhythmias, gastrointestinal disorders, weight changes, and neurological symptoms.\nIt should be prescribed particularly carefully to patients with heart failure or impaired liver function, and blood pressure may gradually decrease even after discontinuing the medication, so it should be used in combination with other antihypertensives under the guidance of a physician.\nThis medication is known not to significantly impair driving or operating machinery, but caution is advised as it may vary by individual.\nWhen taken with other medications, interactions may occur, so especially when combined with certain antibiotics, antihypertensives, analgesics, grapefruit juice, etc., consultation with a physician or pharmacist is necessary.\nDuring pregnancy or breastfeeding, the safety of this medication has not been sufficiently confirmed, so it should be avoided unless under special circumstances, and decisions should be made after consultation with a specialist.\nThis medication can be used in children aged 6 years and older, while its efficacy and safety have not been established in younger ages.\nIn case of overdose, severe hypotension or cardiac problems may occur, and immediate medical attention is required for appropriate treatment.\nLong-term use of this medication has not been reported to increase the risk of cancer or genetic mutation.\nWhen taking this medication, be sure to follow the physician's prescription and instructions, and consult an expert immediately if any abnormal symptoms occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), difficulty breathing, yellowing of the skin (jaundice), severe swelling accompanied by increased blood pressure, severe allergic reactions, severe skin reactions, respiratory issues, liver abnormalities (jaundice)

Mild side effects

Cardiovascular: Flushing, palpitations, hypotension, vasculitis\nGeneral: Fatigue, weakness, lethargy, pain, weight change, edema\nCentral and peripheral nervous system: Dizziness, headache, drowsiness, tension, sensory reduction/sensation abnormality, peripheral neuropathy, fainting, taste disturbance, tremor, extrapyramidal symptoms\nReproductive system: Erectile dysfunction, gynecomastia\nGastrointestinal: Abdominal pain, nausea, changes in bowel habits, dry mouth, dyspepsia, gingival hyperplasia, pancreatitis, vomiting

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from exposure to air and moisture and should be kept at room temperature between 1 to 30 degrees Celsius.\nStoring it this way will help maintain the effectiveness of the medication for a long time.

Appearance and packaging

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.