Medication info

Nokchunja Rasagiline Tablets 1 mg (Rasagiline Mesylate)

Prescription medicationTabletOralApproval withdrawn
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Nokchunja Co., Ltd.
Appearance
Flat round tablets with a white or almost white color
Packaging
For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 202002210 · Approved 2020.03.31

This product's status changed to Approval withdrawn on 2024.06.12. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1 mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5 mg once daily. If it is well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1 mg once daily. This drug may be taken with or without food.

Ingredients

Manufacturer
Nokchunja Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used in the treatment of idiopathic Parkinson's disease. Initially, it can be used alone or administered as an adjunct to dopamine agonists. It can also be used as an adjunct therapy for patients experiencing motor fluctuations during levodopa treatment. This effectively improves the motor symptoms of Parkinson's disease.

How to take

Adult dose

This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1 mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5 mg once daily. If it is well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1 mg once daily. This drug may be taken with or without food.

Precautions

This medication should not be used by individuals who are allergic to specific components. Additionally, caution is needed for those taking other MAO inhibitors, certain analgesics, and several other medications, as using this drug may be risky. It is safer not to administer it to patients with severe liver dysfunction. This medication may cause various side effects such as headache, dizziness, nausea, and skin rashes, so if any unusual symptoms occur, consult a physician immediately. In particular, patients with Parkinson's disease should be wary of mental symptoms such as hallucinations or confusion. This medication may affect blood pressure, so individuals with unstable blood pressure should regularly check it. Caution is needed when driving or operating machinery due to the possibility of drowsiness or sudden sleep. Furthermore, this medication may interact with certain foods or other drugs, so it is essential to consult a physician or pharmacist before taking it. Those who are pregnant or breastfeeding should be careful when taking this medication, and it is advisable for children and the elderly to seek professional advice before use. In cases of overdose, severe side effects may occur, so it is crucial to adhere to the prescribed dosage, and it should be stored in a cool place out of reach of children.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • appetite loss
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal swelling
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urinary urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • trauma
  • weight loss
  • tendinitis
  • movement disorder
  • drowsiness
  • sensory disturbance
  • ataxia
  • muscular hypertonia
  • myasthenia
  • appetite suppression
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • hematoma
  • bleeding
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive shopping or buying
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • low back pain
  • knee joint replacement
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • malignant hyperthermia
  • generalized weakness
  • pulmonary tuberculosis
  • hallucination
  • stupor
  • gait disturbance
  • ocular movement seizure
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • concussion
  • unspecified abrasion
  • laceration
  • scoliosis
  • thirst
  • hypoalbuminemia
  • electrolyte imbalance
  • hematuria
  • increased urination
  • nocturia
  • incontinence
  • vaginitis
  • conjunctival congestion
  • diplopia
  • visual impairment
  • skin thickening
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • excessive secretion
  • irritable bowel syndrome
  • fissured tongue
  • increased frequency of bowel movements
  • unspecified gastrointestinal disease
  • esophagitis
  • excessive gastric acid
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • bowel motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delirium
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • paresthesia
  • tremor
  • freezing phenomenon
  • limb shaking
  • dystonic muscle contractions
  • leg cramps
  • polyuria
  • tremor
  • stuttering
  • dysphonia
  • vocal cord paralysis
  • speech disorder
  • pruritus
  • urticaria
  • abscess
  • hair loss
  • bruise
  • sputum abnormalities
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is advisable to maintain the storage temperature between 1 and 25 degrees Celsius.

Appearance and packaging

Appearance

Flat round tablets with a white or almost white color

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.