Celcox Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding for those who regularly consume more than three glasses of alcohol a day, so patients should definitely consult a doctor or pharmacist. There is a risk of cardiovascular problems, potentially increasing the likelihood of serious cardiovascular events such as myocardial infarction and stroke, hence it should be used at the lowest effective dose for the shortest period of time possible. Serious problems such as perforation, ulcers, or bleeding in the gastrointestinal tract can occur, particularly in the elderly or those with a history of gastrointestinal diseases, requiring extra caution. Those with an allergy to this medication or with certain conditions (severe liver or kidney disease, active peptic ulcer, Crohn's disease, congestive heart failure, etc.) should not take this medication. Patients with liver or kidney function issues, or those with underlying conditions such as hypertension, heart failure, asthma, or diabetes should use this medication with caution and undergo regular monitoring. Dizziness or drowsiness may occur while taking this medication; thus, driving or operating machinery is advised against. This medication can interact with various drugs; if you are taking other medications, be sure to inform your doctor, particularly if taking blood pressure medications, anticoagulants, or antidepressants. Women who are pregnant, potentially pregnant, or breastfeeding should not use this medication, and women planning to conceive should consult a doctor before taking it. For prolonged use, regular blood tests and assessments of liver and kidney function should be carried out, and any unusual symptoms should be immediately reported to healthcare providers. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may appear, and immediate medical attention is necessary. This medication is not recommended for use in children and adolescents, as safety and efficacy have not been established.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of upper and lower gastrointestinal tract, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, taste disturbance, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, osteodystrophy, myalgia, cervical muscle tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle stiffness, reduced hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, angioneurotic edema, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicidality, loss of smell, loss of taste, exacerbation of allergies, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, epistaxis, speech disorders, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, liver dysfunction, angioedema, dermatitis, skin diseases, dry skin, increased sweating, erythema multiforme, sicca syndrome, toxic epidermal necrolysis, generalized bullous fixed drug eruption, fixed drug eruption, vasculitis, acute renal failure, hyponatremia, hepatitis, menstrual disorders, female infertility, chest pain, headache, dizziness, constipation, gastric ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing impairment

This medication should be stored in a tightly closed container to prevent ingress of air or moisture, ideally at room temperature between 15 to 30 degrees Celsius. This helps maintain the medication's efficacy and prevents degradation.

Appearance

A white capsule filled with a white to pale yellow powder with blue markings on both ends.

Package unit

30 capsules/bottle, 100 capsules/bottle