Celecoxib Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg; if necessary, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Patients who regularly consume three or more alcoholic beverages a day must consult a doctor or pharmacist before taking this medication. Heavy alcohol consumption while taking this medicine or other analgesics can increase the risk of gastrointestinal bleeding. This medication can increase the risk of cardiovascular thrombotic events, such as heart attacks or strokes. This risk may be higher with increasing doses and longer duration of use, so it should be taken at the lowest effective dose for the shortest duration necessary. If cardiovascular symptoms such as chest pain, shortness of breath, weakness, or speech difficulties occur during treatment, consult a doctor immediately. Additionally, serious gastrointestinal issues such as perforation, ulcers, and bleeding may occur. This is particularly important for the elderly or those with a history of gastrointestinal disease, and symptoms like epigastric pain, indigestion, black stools, or vomiting should prompt immediate medical attention. This medication should not be administered to patients with certain allergic reactions or severely impaired liver, kidney, heart function, pregnant or breastfeeding women, or those with inflammatory bowel disease. Patients with liver or kidney function impairments, hypertension, asthma, heart failure, diabetes, etc., should exercise particular caution when taking this medication and have their health status regularly monitored as directed by their physician. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. Since this medicine is metabolized in the liver, it may affect liver function; thus, symptoms of liver dysfunction should be reported to a physician immediately. Moreover, this medication may raise blood pressure or worsen existing hypertension, so regular blood pressure monitoring is recommended. There may be interactions with other drugs, so consult a doctor especially when taking antihypertensives, diuretics, anticoagulants, or antidepressants. Pregnant or potentially pregnant women should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. Breastfeeding women should also either discontinue feeding or consult a doctor if taking this medication. The safety for children and adolescents has not been established, so use is not recommended. For long-term use of this medication, regular blood tests and liver and kidney function assessments are necessary, and any unusual symptoms should be reported to a physician promptly. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may appear, requiring immediate medical intervention. Finally, this medication should be kept out of the reach of children, and transferring to other containers should be avoided.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, tension, sensory impairment, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug-induced rash with eosinophilia and systemic symptoms, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, chest pain, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fracture, tendon rupture, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reaction, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, nephrolithiasis, urinary incontinence, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual irregularities, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, hallucinations, pneumonia, dyspnea, epistaxis, voice disorder, vasculitis, anaphylactic reaction, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a temperature between 15 and 30 degrees Celsius when storing the medication. This will ensure that the medication's efficacy is well preserved and safe for use.

Appearance

A white capsule with a blue band at the top and bottom filled with yellowish powder.

Package unit

30 capsules/bottle, 300 capsules/bottle