Megapio Tablet 15mg (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once a day regardless of meals. 1. Monotherapy This medication can be started at a dose of 15 mg once daily as pioglitazone for patients who have not adequately controlled their blood sugar with diet and exercise alone. If sufficient effectiveness is not obtained with the initial dose, it can be increased to 30 mg once daily. 2. Combination therapy - When combined with sulfonylureas,

Child dose

There is no experience of use in children under 18 years of age, so administration is not recommended.

This medication is used for the treatment of type 2 diabetes and acts to improve insulin resistance. It may affect heart function in some patients, so it should not be administered to patients with congestive heart failure or a history of it. If symptoms of heart failure like rapid weight gain, shortness of breath, or swelling occur, a doctor's evaluation should be sought immediately. This medication can cause fluid retention and worsen heart failure, so it should be used with caution in patients with heart disease or edema. Patients with active bladder cancer or a history of bladder cancer should not take this medication, and if hematuria or urinary problems occur, healthcare professionals should be informed immediately. Patients with impaired liver function or severe renal dysfunction need caution with this medication, and regular liver function tests should be conducted during treatment. This medication carries a risk of hypoglycemia, so when used in combination with insulin or other hypoglycemic agents, patients should be well-informed about hypoglycemic symptoms, and dose adjustments of concomitant medications may be necessary. Additionally, this medication may cause weight gain and edema, so patients should periodically monitor weight changes and inform healthcare professionals if edema symptoms worsen. In premenopausal women, this medication may stimulate ovulation, increasing the risk of pregnancy, so appropriate contraceptive measures should be used. Elderly patients or those with compromised renal or liver function require more careful monitoring during use of this medication. Patients receiving this medication should regularly monitor blood sugar and liver function tests, and consult healthcare professionals if any unusual symptoms arise. Drug interactions are possible, so if other medications are being taken, it is essential to inform healthcare professionals, particularly when co-administered with CYP2C8 inhibitors or inducers. Women who are pregnant or may become pregnant should consult with healthcare professionals before using this medication, and breastfeeding women should also decide after consulting experts.

Serious side effects

Congestive heart failure, signs and symptoms of heart failure (including excessive and rapid weight changes, breathlessness, swelling), edema (including peripheral edema, generalized edema, pitting edema, and fluid retention), visible hematuria, urinary dysfunction, urgency, bladder cancer, liver failure, elevated serum ALT levels (greater than three times the upper limit of normal), jaundice, symptoms of liver damage (fatigue, loss of appetite, discomfort in the right upper abdomen, dark urine, jaundice), severe headache, stroke,

Mild side effects

• Headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• upper respiratory infection
• urinary tract infection
• back pain

This medication should be stored in an airtight container that is not exposed to light and kept away from humid places. To maintain the efficacy of the medication, it is best to store it in a cool place between 15 degrees and 30 degrees, especially around 25 degrees.

Appearance

White to grayish round and convex tablet

Package unit

30 tablets/bottle, 300 tablets/bottle