Medication info
NeuBigsagen (Memantine Hydrochloride)

NeuBigsagen (Memantine Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Memantine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
(주)메디카코리아
Appearance
White rectangular film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202002148 · Approved 2020.03.27 · Insurance code 646004930

Summary

Main use
Treatment of moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
This medication is administered orally once a day and should be taken at the same time each day. If necessary, it can be administered twice a day. Dose escalation: The maximum daily dosage is 20mg, increased by 5mg weekly over the first 3 weeks. - First week (Days 1 to 7): 5mg once daily - Second week (Days 8 to 14): 10mg once daily - Third week (Days 15 to 21): 15mg once daily -

Ingredients

Manufacturer
(주)메디카코리아

Efficacy & effects

Treatment of moderate to severe Alzheimer's disease

  • Alzheimer's disease
View approved original text

This medication is used for the treatment of moderate to severe Alzheimer's disease.

How to take

Adult dose

This medication is administered orally once a day and should be taken at the same time each day. If necessary, it can be administered twice a day. Dose escalation: The maximum daily dosage is 20mg, increased by 5mg weekly over the first 3 weeks. - First week (Days 1 to 7): 5mg once daily - Second week (Days 8 to 14): 10mg once daily - Third week (Days 15 to 21): 15mg once daily -

Precautions

This medication should not be used in patients with hypersensitivity to the ingredients or those with severe liver or kidney dysfunction. It must be administered with caution in patients with epilepsy or a history of seizures, and those taking certain NMDA antagonists. In addition, patients expected to have changes in urinary acidity or those with recent heart disease should be careful. When taking this medication, side effects such as dizziness, headaches, constipation, drowsiness, and hypertension may occur. If symptoms worsen, consult a healthcare professional. There may be interactions with other medications, so it is essential to inform your doctor, especially if taking NMDA antagonists, antipsychotic drugs, muscle relaxants, or anticoagulants. Women who are pregnant or breastfeeding should carefully consider the use of this medication, as it may affect the fetus or infant, and discontinuing breastfeeding is recommended. The safety and efficacy of this medication in children or adolescents under 18 years of age have not been established. In cases of overdose, central nervous system symptoms or gastrointestinal symptoms may appear, and immediate medical attention should be sought if suspected. This medication may affect patients' concentration and reaction speed, so caution is advised when driving or operating machinery. Store this medication out of reach of children and keep it in its original container for safety.

Side effects and when to seek care immediately

Serious side effects

Seizures, heart failure, hypertension, venous thrombosis/thromboembolism, shortness of breath, pancreatitis, elevated liver function test values, hepatitis, rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headaches, thunderclap headaches, altered consciousness, visual disturbances

Mild side effects

  • Dizziness
  • headache
  • constipation
  • drowsiness
  • hypertension
  • confusion
  • hallucinations
  • psychiatric reactions
  • balance disorders
  • gait disturbances
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  • seizures
  • heart failure
  • venous thrombosis/thromboembolism
  • shortness of breath
  • vomiting
  • pancreatitis
  • elevated liver function test values
  • hepatitis
  • fatigue
  • restlessness
  • psychosis
  • visual hallucinations
  • stupor
  • unconsciousness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1°C and 30°C to preserve the medication's effectiveness.

Appearance and packaging

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.