Medication info
Dovemarin 250 mg (Dovesil Calcium Hydrate)

Dovemarin 250 mg (Dovesil Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›250mg / 1 tablet
Manufacturer / importer
Donggu Bio Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 202002100 · Approved 2020.03.25 · Insurance code 657308160

Summary

Main use
Treatment of microvascular disorders (diabetic retinopathy, etc.), venous disorders (edema, etc.), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular lesions and retinopathy: 500~1000mg daily 2. Venous disorders: Administer 750mg daily for 1~3 weeks, followed by 500mg daily. Administer after meals with plenty of fluids. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Donggu Bio Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of microvascular disorders (diabetic retinopathy, etc.), venous disorders (edema, etc.), and hemorrhoids

  • Microvascular rupture
  • permeability disorders
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral congestive edema
  • hemorrhoids
View approved original text

This medication is used for vascular-related diseases associated with elevated microvascular rupture and permeability disorders, including vascular damage, diabetic microangiopathy, diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral congestive edema, and hemorrhoids.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular lesions and retinopathy: 500~1000mg daily 2. Venous disorders: Administer 750mg daily for 1~3 weeks, followed by 500mg daily. Administer after meals with plenty of fluids. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication should not be used by individuals allergic to this medicine or its components. This medication contains lactose, so individuals with genetic disorders such as galactose intolerance, lactose deficiency, or glucose-galactose absorption disorders should also not use this medication. Patients with poor kidney function should exercise caution when using this medication, especially those with severe kidney disease requiring dialysis may need to reduce the dosage of the drug. Patients with impaired liver function should also use this medication cautiously, and if liver values increase, the therapeutic effects and risks should be reevaluated. This medication contains sodium bisulfite, which may cause allergic reactions or asthma attacks, so caution is advised for patients with asthma or hypersensitivity to sulfites. During the use of this medication, symptoms such as headache, abdominal pain, nausea, diarrhea, vomiting, arthralgia, and myalgia may occur, and liver values may also rise. Rarely, severe side effects such as a decrease in blood cell count may occur, so if high fever or symptoms of infection are present, consult a doctor immediately. If hypersensitivity reactions or skin rashes, facial swelling occur, discontinue the medication and inform medical personnel. Effects on driving or operating machinery are unknown, but caution is needed depending on symptoms. It is advisable to avoid this medication during pregnancy, and it is not recommended during breastfeeding since small amounts may be secreted in breast milk. Safety in children has not been adequately confirmed, so it should be administered cautiously to children. This medication may affect blood test results, so it is important to inform medical personnel before testing. No specific symptoms have been reported for overdose, but if anomalies occur, immediate emergency treatment should be received.

Side effects

  • Agranulocytosis
  • Neutropenia
  • Leukopenia
  • Skin rash
  • Allergic dermatitis
  • Itching
  • Urticaria
  • Facial edema
  • Anaphylactic reaction
  • Headache
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  • Abdominal pain
  • Nausea
  • Diarrhea
  • Vomiting
  • Increased alanine aminotransferase
  • Arthralgia
  • Myalgia
  • Fever
  • Chills
  • Apathy
  • Fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius. Proper storage ensures the medication retains its efficacy for a longer time.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.