Rosabesil Tablet 5/100 mg (Amlodipine, Losartan Potassium)

Adult dose

The recommended dosage for this medication is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time daily (e.g., in the morning). Typically, 5/50 mg of this medication is taken once daily; if blood pressure is not adequately controlled after 2 weeks, the dosage may be increased to 10/50 mg taken once daily.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years of age, and thus the administration of this medication is not recommended.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately once pregnancy is confirmed. It may also pose risks to the fetus if taken in early pregnancy; therefore, women who may become pregnant should consult with a doctor. Patients with decreased effective blood volume, particularly those on diuretics, may experience symptoms of hypotension when first taking this medication, so caution is necessary. This medication should not be given to patients allergic to its active ingredients or related components, patients with severe liver dysfunction, severe aortic stenosis, or those in a state of shock. Patients with high potassium levels in the blood, severe kidney impairment, and those on strict salt restrictions should use this medication cautiously and require regular monitoring. This medication may cause side effects such as dizziness or drowsiness, so caution should be exercised when performing hazardous tasks like operating machinery or driving. Patients with impaired liver or kidney function should adjust the dosage or avoid use of this medication. If used with other antihypertensive agents, blood pressure may drop too low, so it should be taken as directed by a physician. This medication should be avoided with grapefruit juice as it may increase blood concentration. It is safest for pregnant or breastfeeding women to avoid this medication, and those planning pregnancy or suspecting they may be pregnant should consult with healthcare professionals. Safety and efficacy for pediatric and adolescent patients have not been established, so its use is not recommended. Elderly patients may require initial dose adjustments, so they should follow the instructions of their healthcare provider. In cases of overdose, severe hypotension and cardiac issues can occur, so immediate medical attention is required. This medication should be stored out of reach of children, and it is advisable not to transfer the medication to another container.

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, wheezing or difficulty breathing, asthma attack, respiratory symptoms accompany cough and fever, jaundice (yellowing of the skin or eyes), severe malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Dizziness
• headache
• drowsiness
• weakness
• chest discomfort
• chest pain
• early satiety
• peripheral edema
• pit edema
• abdominal discomfort

This medication must be stored in a tightly closed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to ensure the medication’s effectiveness is preserved safely.

Appearance

Light pink, rectangular film-coated tablet

Package unit

30 tablets/bottle