Lasto 10 mg (Lafutidine)

Adult dose

1. Short-term treatment of gastric ulcers The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks; however, the healing period may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks; however, the healing period may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks; however, the healing period may occasionally vary from patient to patient. 4. Antibiotic combination therapy in patients with peptic ulcers infected with Helicobacter pylori Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication The usual dose is 10mg of lafutidine per dose, administered orally twice (the night before surgery at bedtime and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis Administer 10mg of lafutidine per dose orally twice daily.

This medication should not be used by individuals allergic to any of its ingredients. It contains lactose, so patients with congenital disorders of galactose intolerance should not take it. Those with a history of drug allergies, liver or kidney function issues, patients undergoing dialysis, and the elderly should use this medication with caution. While taking this medication, side effects such as severe allergic reactions, liver function abnormalities, and decreases in blood cell counts can occur; therefore, symptoms should be monitored carefully. If symptoms such as facial pallor, low blood pressure, and difficulty breathing occur, immediately discontinue the medication and seek medical attention. If symptoms of liver function abnormalities arise, stop taking the medication and receive appropriate treatment. Discontinue use if blood tests show a decrease in white blood cells or platelets. Additionally, rare but serious side effects such as skin rashes, seizures, heart problems have been reported, so report any unusual symptoms to healthcare professionals immediately. Mild side effects may include abdominal pain, diarrhea, headaches, insomnia, and dizziness, so please keep this in mind. This medication may mask the symptoms of malignant tumors; thus, accurate examinations should be conducted if symptoms such as weight loss, recurrent vomiting, or bleeding occur. Particularly, if gastric cancer is suspected, the medication should be discontinued after initial tests confirm malignant gastric cancer. During treatment, the condition should be monitored closely, and if ineffective, alternative treatment methods may be considered. For geriatric patients, it should be used with caution, adjusting dosage and frequency due to decreased physical function. Patients on dialysis may experience increased blood drug concentrations, so initiate treatment with a lower dosage. Women who are pregnant or may become pregnant should take this medication based on a careful evaluation of its benefits and risks under a doctor's guidance. Breastfeeding women should refrain from taking this medication since it can be secreted in breast milk. Safety has not been established in children, so it is not recommended for use in pediatric patients. Store this medication out of reach of children, in its original container, and do not transfer it to other containers to ensure safety. Animal studies have shown no carcinogenicity, but changes in certain neuroendocrine cells have been observed at high doses. High-dose administration during pregnancy has been associated with some side effects; however, no fetal malformations have been reported.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized pruritus
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngodynia

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is between 1°C and 30°C at room temperature. Proper storage will help maintain the medication's effectiveness and safety over time.

Appearance

White circular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle