Dobes Tablet (Dobesilic Acid Calcium Hydrate)

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular disorders and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used by patients who are allergic to this medication or any of its ingredients. This medication contains lactose and should not be administered to patients with a genetic condition that prevents lactose digestion. Caution is advised for patients with poor kidney function, and particularly in severe kidney impairment requiring dialysis, the dosage may need to be reduced. Patients with liver dysfunction also require caution, and if liver enzyme levels increase, the therapeutic benefits and risks must be reassessed. This medication contains sulfites, which may cause allergic reactions or asthma attacks in sensitive patients, particularly those with asthma. While taking this medication, if symptoms of infection such as high fever, mouth inflammation, or sore throat appear, the doctor must be informed immediately, and the medication may need to be stopped after verification through blood tests. If a severe allergic reaction occurs, discontinue use immediately and inform healthcare professionals. Common symptoms during treatment may include headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, and muscle pain; however, most recover after discontinuation of the medication. If skin rashes, itching, or facial swelling occur, treatment must be discontinued. Due to limited experience with this medication during pregnancy, it is recommended to avoid its use, and it should be avoided during breastfeeding as well since it is minimally secreted into breast milk. Safety in pediatric populations has not been sufficiently studied, thus caution is advised for use in children. For elderly individuals aged 65 and above, there are no special precautions, but the general health condition should be considered when using the medication. Since this medication may affect blood test results, it is advisable to collect test samples before treatment. No specific symptoms have been reported in cases of overdose; however, if an overdose is suspected, emergency medical care should be sought immediately.

• Agranulocytosis
• neutropenia
• leukopenia
• skin rash
• allergic dermatitis
• pruritus
• urticaria
• facial edema
• anaphylactic reaction
• headache

This medication must be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is recommended to store the medication at room temperature between 1 and 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 90 tablets/bottle