Medication info
Megaclufenac Tablets (Acclofenac)

Megaclufenac Tablets (Acclofenac)

Prescription medicationTablet경구
Ingredient · strength
Aceclofenac›100mg / 1 tablet
Manufacturer / importer
(주)엘앤씨바이오
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 202001890 · Approved 2020.03.18 · Insurance code 060500010

Summary

Main use
Relief of inflammation and pain in rheumatoid arthritis, ankylosing spondylitis, etc.
Who takes it
Adults
Adult dose
As Acclofenac, take 100 mg twice a day every 12 hours. This medication should be taken whole, not chewed or crushed. Adjust the dosage as needed according to symptoms. To minimize the cardiovascular side effects of this medication, it should be administered at the lowest effective dose for the shortest duration.

Ingredients

Manufacturer
(주)엘앤씨바이오

Efficacy & effects

Relief of inflammation and pain in rheumatoid arthritis, ankylosing spondylitis, etc.

  • Rheumatoid arthritis
  • ankylosing spondylitis
  • osteoarthritis
  • periarthritis of the scapulohumeral joint
  • toothache
  • inflammation
  • back pain
  • sciatica
  • pain due to non-articular rheumatism
View approved original text

Hello. This medication is used for inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, osteoarthritis (degenerative arthritis), and periarthritis of the shoulder. It is also effective for alleviating pain caused by toothaches or inflammation from trauma, back pain, sciatica, and pain due to non-articular rheumatism. It helps improve these various inflammatory and painful conditions. Therefore, this medication is used for the treatment of inflammation and related pain in joints and soft tissues.

How to take

Adult dose

As Acclofenac, take 100 mg twice a day every 12 hours. This medication should be taken whole, not chewed or crushed. Adjust the dosage as needed according to symptoms. To minimize the cardiovascular side effects of this medication, it should be administered at the lowest effective dose for the shortest duration.

Precautions

This medication may cause serious side effects such as gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic beverages daily, so it is essential to consult with a doctor or pharmacist. This medication carries a risk of causing problems with the heart or blood vessels, so individuals with risk factors such as cardiovascular disease, hypertension, diabetes, or smoking should carefully consider whether to take it. The longer the dosage and duration of use, the greater the cardiovascular risk, so it is advisable to take the lowest effective dose for the shortest duration possible. This medication may cause gastrointestinal issues such as bleeding, ulcers, or perforations, so particular caution is required during use, especially for the elderly or those with a history of gastrointestinal disorders. It should not be taken if there is an active peptic ulcer or bleeding, or if there is hypersensitivity to this medication or similar drugs. Individuals with a history of asthma or allergic reactions should also exercise caution when taking this medication, as should those with congestive heart failure or severe kidney or liver impairment. Pregnant women in the late stages of pregnancy or breastfeeding should not take this medication, and caution is advised during the first or second trimesters. Various side effects may occur during use, such as dizziness, skin rashes, gastrointestinal disorders, and liver dysfunction, so if any symptoms arise, immediate consultation with a healthcare professional is recommended. This medication may interact with other drugs, so if taking blood pressure medications, diuretics, anticoagulants, or antidiabetic medications, it is essential to discuss with a doctor. Women planning pregnancy should avoid this medication as it may affect fertility. If experiencing symptoms such as dizziness or drowsiness, it is advisable to refrain from driving or operating hazardous machinery. The safety of this medication has not been established for children and adolescents, so its use in this age group is not recommended. Elderly individuals are at a higher risk of gastrointestinal bleeding and perforation, so special caution should be exercised when taking this medication. In case of overdose, symptoms such as gastrointestinal irritation, hypotension, respiratory depression, and seizures may occur, and immediate medical attention should be sought. This medicine should be kept out of reach of children, and transferring it to other containers should be avoided as it may adversely affect the quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), severe allergic reactions, shock, anaphylactic reactions, severe rash accompanied by high fever, blisters, skin peeling, pain in mouth/eyes mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues associated with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver problems (jaundice), sudden and severe headache,

Mild side effects

  • Dizziness
  • abnormal liver enzyme levels
  • itching
  • rash
  • skin reactions
  • anemia
  • hyperkalemia
  • depression
  • unusual dreams
  • insomnia
Show 28 more
  • visual disturbances
  • optic neuritis
  • sensory abnormalities
  • tremors
  • drowsiness
  • headache
  • taste disturbances
  • neck stiffness
  • fever
  • spatial disorientation
  • confusion
  • hallucinations
  • tinnitus
  • fatigue
  • palpitations
  • facial flushing
  • hypertension
  • heart failure
  • difficulty breathing
  • bronchospasm
  • wheezing
  • dyspepsia
  • abdominal pain
  • nausea
  • diarrhea
  • abdominal bloating
  • gastritis
  • stool changes

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius. This way, the efficacy and safety of the medication can be well-preserved.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.