Medication info

Espenac Beta Injection (Diclofenac β-Dimethylaminoethanol)

Prescription medicationInjectionsExpired
Ingredient · strength
Diclofenac Beta-Dimethylaminoethanol›45mg / 1mL
Manufacturer / importer
삼성제약(주)
Appearance
A brown ampoule injection containing a clear pale yellow solution
Packaging
50 ampoules/box [(2 milliliters/ampoule)]
Approval status
Expired

MFDS item code 202001746 · Notified 2020.03.13

This product's status changed to Expired on 2025.03.13. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of inflammation and pain due to rheumatoid arthritis and osteoarthritis (degenerative joint disease), etc.
Who uses it
Adults
Adult dosage
As diclofenac beta-dimethylaminoethanol, 90mg is injected deeply into one side of the upper buttocks once daily. In severe cases, 90mg can be administered twice a day, alternating injections into both buttocks. After initial treatment, it is changed to oral tablets or suppositories. Adjustments should be made depending on age, disease, and symptoms. To minimize cardiovascular adverse reactions of this medication, it should be used at the minimum effective dose for the shortest duration.

Ingredients

Manufacturer
삼성제약(주)

Efficacy & effects

Relief of inflammation and pain due to rheumatoid arthritis and osteoarthritis (degenerative joint disease), etc.

  • Rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • post-traumatic inflammation
  • post-surgical inflammation
  • pain
  • acute gout
  • renal colic
  • hepatic colic
View approved original text

This medication is used for chronic inflammatory joint diseases such as rheumatoid arthritis, osteoarthritis (degenerative joint disease), and ankylosing spondylitis. It is also effective in alleviating inflammation and pain occurring after trauma or surgery, acute gout, and pain around the kidneys and liver. It helps improve patients' symptoms by providing relief from various inflammatory diseases and pain.

Dosage and Administration

Adult dosage

As diclofenac beta-dimethylaminoethanol, 90mg is injected deeply into one side of the upper buttocks once daily. In severe cases, 90mg can be administered twice a day, alternating injections into both buttocks. After initial treatment, it is changed to oral tablets or suppositories. Adjustments should be made depending on age, disease, and symptoms. To minimize cardiovascular adverse reactions of this medication, it should be used at the minimum effective dose for the shortest duration.

Precautions

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three glasses of alcohol per day, so it is essential to consult a doctor or pharmacist. Those with cardiovascular issues or risk factors should be cautious as serious cardiovascular problems such as myocardial infarction and stroke may occur while taking this medication. This medication can cause serious issues such as gastrointestinal bleeding, ulcers, and perforation, so elderly patients or those with a history of gastrointestinal diseases should monitor their symptoms closely while taking it. In cases of severe allergic reactions, it may affect the heart, so if chest pain or allergic symptoms occur, medical personnel should be notified immediately. Injectable medication in ampoule form can have glass fragments when cut, so special care should be taken when used by children or the elderly. Products containing benzyl alcohol can be dangerous for premature infants, so caution is needed when using such products. Individuals with peptic ulcers, severe blood disorders, liver or kidney dysfunction, hypertension, or heart failure should not take this medication. Those with allergies to aspirin or other non-steroidal anti-inflammatory drugs, or with a history of asthma, should also avoid taking it. Extra caution should be exercised when administering this medication to individuals with gastrointestinal diseases, blood disorders, liver or kidney issues, hypertension, asthma, the elderly, or children. Rarely, this medication can cause various side effects such as shock, gastrointestinal bleeding, skin rashes, liver dysfunction, kidney dysfunction, hypersensitivity, neuropsychiatric symptoms, etc., so if there are abnormal symptoms, medical personnel should be notified immediately. Regular blood tests and liver and kidney function tests should be performed during long-term use, and if any abnormal symptoms appear, discontinue the medication and consult a doctor. This medication may worsen hypertension and can cause fluid retention or heart failure symptoms, so careful observation is necessary for those with related diseases. During pregnancy, especially in later stages, it may pose risks to the fetus, so it should be avoided, and the use of this medication should be considered very carefully for women of childbearing age. If breastfeeding, consideration should be given to whether to stop nursing or discontinue the medication since this drug can be passed into breast milk and affect the baby. The risk of side effects may increase when this medication is combined with other non-steroidal anti-inflammatory drugs or certain medications, so if you are taking any other drugs, be sure to inform your doctor. The elderly and children should take the minimal effective dose with extra caution and pay special attention to the occurrence of side effects.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock (chest pain, coldness, shortness of breath, limb paresthesia, low blood pressure, swelling, rash, itching), Stevens-Johnson syndrome, Lyell's syndrome, jaundice, acute renal failure, asthma attacks, severe edema, edema accompanied by increased blood pressure, severe allergic reactions, severe skin adverse reactions, respiratory issues, liver problems (jaundice), serious neurological symptoms, severe edema, or urinary issues

Mild side effects

  • Loss of appetite
  • nausea
  • vomiting
  • abdominal pain
  • diarrhea
  • stomatitis
  • dry mouth
  • constipation
  • headache
  • drowsiness
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  • dizziness
  • insomnia
  • nervousness
  • tingling
  • confusion
  • hallucination
  • seizures
  • blurred vision
  • tinnitus
  • increased blood pressure
  • decreased blood pressure
  • palpitations
  • tachycardia
  • general fatigue
  • sweating
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a tightly sealed container that can block light. Additionally, the medication should be kept at room temperature, avoiding very hot or very cold places, ideally between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

A brown ampoule injection containing a clear pale yellow solution

Package unit

50 ampoules/box [(2 milliliters/ampoule)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.