Medication info

New Cotidine 10mg (Lansoprazole)

Prescription medicationTabletExpired
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Saehan Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Expired

MFDS item code 202001696 · Approved 2020.03.11

This product's status changed to Expired on 2025.03.11. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); pre-anesthetic medication; combination therapy for eradication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Ingredients

Manufacturer
Saehan Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); pre-anesthetic medication; combination therapy for eradication

  • Gastric ulcer
  • duodenal ulcer
  • mucosal lesions of acute and chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat gastric ulcer and duodenal ulcer. It also helps to improve gastric mucosal lesions in patients with acute and chronic gastritis. It is used in combination with antibiotics for the treatment of peptic ulcers caused by Helicobacter pylori infection, and is also utilized for pre-anesthesia dosing. Furthermore, it is effectively used to treat gastroesophageal reflux disease. It is useful for a variety of gastrointestinal disorders, improving the symptoms of patients.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Precautions

This medication should not be used by individuals who are allergic to its ingredients. It also contains lactose, so people with lactose intolerance or certain genetic conditions should avoid taking it. Patients with a history of drug allergies, those with liver or kidney function issues, patients undergoing dialysis, and the elderly should use this drug with caution. This medication can rarely cause severe allergic reactions, so if symptoms such as pale face, low blood pressure, and difficulty breathing occur, discontinue use immediately and seek medical attention. Liver dysfunction or jaundice symptoms may appear, so periodic liver function tests are necessary, and usage should be stopped if abnormalities are found. Blood-related issues, such as leukopenia or thrombocytopenia, can occur, so consult a doctor immediately if these symptoms appear. This medication may have various side effects including indigestion, headache, dizziness, insomnia, etc., and should be reported if abnormal symptoms occur. Especially in cases of suspected malignant tumors, this medication may conceal symptoms or delay diagnosis, so professional examination is essential. Elderly individuals have decreased physical functions and should use the medication carefully, adjusting the dosage and administration intervals. Patients undergoing dialysis may have elevated blood drug concentrations, so treatment should start with a low dose and be taken with caution. Women who are pregnant or may become pregnant should use this medication only when the benefits outweigh the risks as determined by a physician, and breastfeeding women are advised not to take it as it may be excreted in breast milk. Safety in children has not been sufficiently confirmed, so administration to children is not recommended. This medication should be kept in a safe place out of reach of children and stored in its original container to prevent misuse or quality deterioration.

Side effects

  • Shock
  • anaphylaxis symptoms
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • hepatic impairment
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • generalized malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell syndrome
  • rhabdomyolysis
  • atrioventricular block
  • contractile failure
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • anorexia
  • headache
  • insomnia
  • drowsiness
  • reversible confusion state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • chills
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • prolonged life span
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • malaise
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • distension
  • rhinopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • cough
  • oral-pharyngeal pain
  • oral-pharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • neck pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine must be stored in a tightly sealed container to protect against exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.