Medication info

Inirapatidin Tablet 10mg

Prescription medicationTabletExpired
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Vivozon Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 202001693 · Approved 2020.03.11

This product's status changed to Expired on 2025.03.11. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); pre-anesthetic medication; adjunctive treatment for Helicobacter pylori eradication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Ingredients

Manufacturer
Vivozon Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); pre-anesthetic medication; adjunctive treatment for Helicobacter pylori eradication

  • Gastric ulcer
  • duodenal ulcer
  • mucosal lesions in acute and chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medicine is used for the treatment of gastric ulcers and duodenal ulcers. It also improves gastric mucosal damage caused by acute and chronic gastritis, enhancing the therapeutic effect when used in combination with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection. It can be safely administered before anesthesia, and also helps in the treatment of gastroesophageal reflux disease. Overall, it is used for the treatment and symptom improvement of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

Precautions

This medication should not be used by those allergic to any of its ingredients. Additionally, as it contains lactose, individuals with genetic issues such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should avoid taking this medication. Patients with a history of drug allergies or issues with liver or kidney function, those undergoing dialysis, and elderly patients should be particularly cautious when using this medication. This medication can rarely cause severe allergic reactions, liver dysfunction, and significant side effects such as a decrease in blood cell count, so symptoms should be closely monitored, and if any abnormalities occur, usage should be discontinued immediately and a doctor consulted. Mild side effects such as constipation, diarrhea, headache, dizziness, and fatigue may occur in some patients, so it is important to monitor one’s condition closely. If a malignant tumor is suspected, as this medication may conceal symptoms or delay diagnosis, comprehensive tests should be conducted, and if diagnosed with malignant gastric cancer, this medication should be discontinued. During treatment, regular monitoring of the patient's blood, liver, and kidney functions should be conducted while using the minimum effective dose, and if there is no effect, a different treatment method should be adopted. Elderly patients may have reduced bodily functions and should take this medication with careful adjustments to dosage and administration intervals. For patients undergoing dialysis, blood drug concentration may increase, so they should start with a low dose and proceed cautiously. Pregnant women or those who may become pregnant should use this medication only under a doctor's judgment, and nursing mothers are advised against taking this medication since it can be excreted in breast milk. Safety in children has not been established, so it should be used cautiously in pediatric patients. This medication should be kept out of the reach of children and stored in its original container to maintain drug quality and prevent misuse.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • liver dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
Show 83 more
  • general malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell's syndrome
  • rhabdomyolysis
  • heart block
  • reduced contractility
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • disturbance of consciousness
  • dizziness
  • fever
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • prolonged life
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • malaise
  • glossitis
  • headache
  • chest pain
  • subdural hematoma
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • nasopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid artery stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • joint pain
  • neck pain
  • itching
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.