Sevicock Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted for each patient, and it may be taken regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who consume large amounts of alcohol daily; thus, consultation with a doctor or pharmacist is essential. Individuals with heart or vascular issues or risk factors may have a higher risk of cardiovascular complications such as myocardial infarction and stroke when taking this medication, so it should be used at the minimum dose for a short duration only. Individuals with a history of ulcers or gastrointestinal bleeding should be closely monitored for the occurrence of gastrointestinal perforation or bleeding while on this medication, and immediate treatment should be sought if symptoms arise. This medication should not be used in individuals with specific allergic reactions, severe liver or kidney impairment, women who are pregnant or breastfeeding, or those with a history of heart failure or cardiovascular diseases. Caution is advised when using this medication in individuals with liver or kidney problems, asthma, hypertension, or diabetes, and regular monitoring should be carried out to check their condition. This medication may have various side effects, including dyspepsia, headache, dizziness, skin rash, hypertension, and gastrointestinal disturbances. Consultation with healthcare professionals is necessary if abnormal symptoms occur. Since this medication is metabolized in the liver, caution is required when taken with other medications that affect liver function, and dosage adjustments may be necessary due to interactions that can change blood levels of some drugs. Women who are pregnant or planning to become pregnant should avoid this medication, and if pregnancy is confirmed while on the medication, it should be discontinued immediately and a doctor should be consulted. It is also advisable for breastfeeding women to avoid this medication, and safety in children and adolescents has not been established. Elderly patients may have reduced kidney and liver function, so special monitoring and caution are needed during administration. Regular blood tests and liver and kidney function tests should be performed to check for abnormalities during the course of this medication, and healthcare providers should be notified promptly of any unusual symptoms. Overdosage may present with symptoms such as vomiting, drowsiness, and nausea, and appropriate treatment may be required depending on the symptoms. This medication should be stored in a safe place out of reach of children, and transferring it to other containers should be avoided.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, worsening of allergies, allergic reactions, lethargy, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, female infertility, chest pain, wound infection, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, hearing loss, ear abnormalities, ear pain, hearing impairment, liver dysfunction, increased ALT, increased AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon ruptures, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, embolism, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis

This medication should be kept in a tightly sealed container to prevent air and moisture infiltration and stored in a cool place between 15°C and 30°C. This storage method helps maintain the efficacy of the medication for a longer period and prevents deterioration.

Appearance

A white capsule filled with powder, ranging from white to light yellow, with blue stripes on both ends.

Package unit

30 capsules/bottle, 100 capsules/bottle