Lapuni Tablet (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials lasting up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials lasting up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. In clinical trials lasting up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary from patient to patient. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

This medication should not be used by patients who have allergic reactions to this medication's components. This medicine contains lactose, so it is advisable for patients with hereditary diseases that prevent lactose digestion to avoid taking it. Patients who have had hypersensitivity reactions to medications, those with liver or kidney function problems, patients on dialysis, and the elderly should use this medication with increased caution. During the therapy, serious allergic reactions or symptoms of liver dysfunction or blood abnormalities may appear, necessitating immediate cessation of the medication and consultation with healthcare professionals. Milder side effects like headaches, indigestion, nausea, and abdominal bloating may also occur, and if any unusual symptoms persist, the patients should notify their physician. If a malignant tumor is suspected, this medication could mask symptoms or hinder diagnosis; thus, necessary examinations should be performed, and if malignant gastric cancer is confirmed, the medication should be discontinued. Elderly patients may require dose adjustments and careful monitoring due to reduced physical function. Patients on dialysis may experience elevated drug concentration in the blood and should start with a low dose and administer it cautiously. Pregnant women should use this medication only when necessary based on a physician's judgment, and nursing mothers are advised not to take it, as it may be secreted in breast milk. The safety of this medication in children has not been sufficiently established; therefore, its use in children is discouraged. This medication should be stored out of reach of children and kept in its original container to prevent misuse or quality deterioration.

• Shock
• symptoms of anaphylaxis
• pallor
• hypotension
• generalized rash
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle