Megacoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or take 100 mg twice daily in divided doses. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who regularly consume more than three glasses of alcohol per day, so consultation with a doctor or pharmacist is essential. This medication may increase the risk of serious cardiovascular events such as cardiovascular thromboembolism, myocardial infarction, and stroke, so it should be used at the lowest effective dose and for the shortest duration, with careful observation for cardiovascular symptoms. This medication may increase the risk of gastrointestinal perforation, ulcers, or bleeding; therefore, individuals with a history of gastrointestinal disease or elderly individuals should exercise extreme caution, and if symptoms such as abdominal pain, dyspepsia, black stools, or hematemesis occur, they should notify medical personnel immediately. This medication should not be administered to individuals with a history of certain allergies, severe liver or kidney impairment, active peptic ulcer, congestive heart failure, pregnant women, or breastfeeding mothers. Patients with a history of liver disease, kidney disease, asthma, hypertension, diabetes, or cardiovascular disease, as well as the elderly, should be administered this medication with caution and may require regular monitoring. While taking this medication, side effects such as headache, dizziness, dyspepsia, skin rash, itching, swelling, hypertension, and cough may occur, so symptoms should be monitored, and any abnormalities should be discussed with medical personnel. Particularly, this medication can affect liver and kidney function, so regular blood tests as well as liver and kidney function tests are important. This medication can interact with various drugs, so individuals taking other medications should inform their medical personnel, as dose adjustments or discontinuation may be necessary. Women who are pregnant or planning to become pregnant should avoid taking this medication and breastfeeding mothers are also advised to refrain from using it. Elderly patients may have a higher risk of side effects due to decreased bodily functions, so extra caution is needed when administering this medication; if they have a low body weight, treatment should start at a lower dosage. Dizziness or drowsiness may occur when taking this medication, so it's safer to avoid driving or operating machinery. In the event of an overdose, symptoms such as vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children, and care should be taken to avoid transferring it to another container as this may cause a decline in quality or lead to accidents.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illnesses, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, NAG elevation, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorder, chest pain, hallucinations, cerebral hemorrhage, aseptic meningitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash associated with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease nephritis, anaphylactic reaction, vasculitis, bullous dermatitis, vasculitis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, headache, leg cramps, tension increase, sensory decline, migraine, neuralgia, neuropathy, sensory abnormalities, ataxia, suicide, anosmia, ageusia, anorexia, hyperphagia, depression, neural hyper-reactivity, somnolence, seizure exacerbation, confusion, upper respiratory tract infections, herpes simplex, wound infections, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasms, dysmenorrhea, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholecystitis, jaundice, liver necrosis, liver failure, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, elevated LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, epistaxis, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, contact dermatitis, injection site reactions, skin nodules

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and it should be kept at room temperature between 15 and 30 degrees Celsius for safe storage. Storing it this way can maintain the medication's efficacy for a longer period.

Appearance

A capsule filled with white to light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle