Amantine Tablets (Memantine Hydrochloride)

Adult dose

Treatment must be initiated by a physician experienced in the diagnosis and treatment of Alzheimer's dementia, and only if a caregiver can regularly verify the patient's medication intake. This medicine can be taken irrespective of food intake. Dose increase: The maximum daily dose is 20 mg, and to minimize the risk of adverse reactions, the dosage should be gradually increased by 5 mg each week over the first 3 weeks to reach the maintenance dosage.

This medicine should not be used in patients with allergies to any of its components. It is also safe not to administer it to patients with severely impaired liver function or severely reduced kidney function. Caution is needed when using this medicine in patients with a history of epilepsy or seizures, or those prone to seizures. Taking this medicine together with other medications that have similar effects may increase the risk of side effects, so it is advisable not to combine them. In situations where the acidity of urine may change or there is a change in dietary habits, it should be carefully monitored under the doctor's guidance. Patients with heart disease or uncontrolled hypertension must consult their doctor before taking this medicine. This medicine may cause side effects such as dizziness, headache, constipation, drowsiness, and hypertension, so any unusual symptoms should be reported. Symptoms such as mental confusion or hallucinations may occur rarely, and if they appear, medical staff should be informed immediately. It may interact with other medications, so particularly inform the doctor if taking antipsychotics, muscle relaxants, anticoagulants, etc. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this medicine, and breastfeeding women are recommended to discontinue breastfeeding. The safety and efficacy of this medicine in children or adolescents under the age of 18 have not been established. In case of overdose, symptoms such as confusion, drowsiness, hallucinations, and seizures may occur, requiring immediate medical attention. This medicine may affect the ability to drive or operate machinery, thus caution is necessary. Finally, it is safest to keep this medicine out of the reach of children and not to transfer it to another container.

Serious side effects

• Seizures
• hallucinations
• psychiatric reactions
• heart failure
• hypertension
• venous thromboembolism
• shortness of breath
• pancreatitis
• hepatitis
• coma

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• fungal infections
• drug hypersensitivity reactions
• confusion
• hallucinations
• psychiatric reactions

This medicine may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius to preserve the medicine's efficacy.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle