InjenTa Duo Tablets 2.5/500 mg

Adult dose

This medication is administered twice daily with meals. 1. If currently not being treated with metformin: The initial dose is to take this drug 2.5/500 mg twice daily, one tablet at a time, and can be increased to 2.5/1000 mg twice daily, one tablet at a time. 2. When switching from a combination therapy of linagliptin and metformin: Patients previously taking linagliptin and metformin at the same dosage are to start this medication at the same dosage.

This medication may cause a rare but serious side effect known as lactic acidosis, so caution is needed. Lactic acidosis occurs when there is a buildup of lactic acid in the body, which can be life-threatening if not treated. Individuals allergic to this drug's active ingredients or any components should not take it. Type 1 diabetes patients, those with lactic acidosis or diabetic ketoacidosis, and people with severe renal impairment should also avoid this medication. Avoid this drug if you have conditions that can affect kidney function, such as severe infections, dehydration, or acute myocardial infarction. Patients with impaired liver function or gastrointestinal disorders should refrain from using this drug. Pregnant or breastfeeding women are advised not to use this drug. When using this medication in conjunction with other blood glucose-lowering agents, caution is necessary due to the risk of hypoglycemia. Particularly when combined with sulfonylureas or insulin, the risk of hypoglycemia may increase and dose adjustments may be needed. The usage and dosage of this drug should be adjusted based on kidney function, and regular kidney function tests are necessary. This medication may need to be temporarily discontinued before and after acute illnesses or surgeries, so follow your doctor's instructions. If you experience sudden abdominal pain, muscle weakness, difficulty breathing, or lethargy while taking this drug, go to the hospital immediately. This drug may lower vitamin B12 levels, thus vitamin B12 testing may be required during long-term use. It is advisable to avoid alcohol consumption while taking this medication, as alcohol can increase the risk of lactic acidosis. If iodine contrast media is to be used during radiological examinations, this drug should be discontinued before and after the test and kidney function must be checked. The elderly should take this medication with particular caution due to the potential for reduced kidney function, and dosage adjustments and regular testing are needed. This medication is not recommended for children or adolescents as safety and effectiveness have not been sufficiently proven. If skin blisters or rashes occur while taking this medication, consult your doctor immediately. In case of overdose, the risk of lactic acidosis increases, so it is essential to adhere to the prescribed dosage, and immediate medical attention is required in the event of overdose.

Serious side effects

Urticaria, angioedema, lactic acidosis, blistering similar to pemphigus, acute pancreatitis, liver function abnormalities (abnormal liver function tests, hepatitis), angina, acute myocardial infarction, unstable angina, cardiac arrest, heart failure (congestive heart failure), difficulty breathing, asthma, pneumonia, cerebral infarction, acute kidney injury, end-stage renal disease, fever, discomfort in the chest, headache, confusion of consciousness, visual disturbances, paralysis, hypoglycemia (when linagliptin/metformin is combined with sulfonylureas)

Mild side effects

Nasopharyngitis, various gastrointestinal disorders (loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, stomatitis), reduced and deficient vitamin B12 levels, taste disturbances, cough, pruritus, rash, increased blood triglycerides, increased amylase, angioedema, indigestion, anxiety, depression, dizziness, drowsiness, itching, lightheadedness, headache, insomnia, fever, pain, discomfort in the chest, weakness, chest pain, voice disorders, runny nose,

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1 degree and 30 degrees Celsius at room temperature. This will help maintain the drug's effectiveness longer.

Appearance

Biconvex oval film-coated tablet in bright yellow color

Package unit

60 tablets/box [10 tablets/PTP Χ 6]