Glarinduo Tablet 2.5/500mg

Adult dose

The dosage of this medication should not exceed the maximum recommended doses of Linagliptin 2.5 mg and Metformin 1000 mg taken twice daily, and should be determined based on the patient's current treatment regimen, efficacy, and tolerability. This medication is administered twice daily with meals. 1. For those currently not receiving treatment with Metformin: The initial dosage of this medication is 2.5/500 mg taken twice daily, 1 tablet at a time.

This medication is primarily used to control blood sugar. One of the ingredients in this medication can cause a serious condition known as lactic acidosis, so individuals with certain health conditions should not take this medication. For example, patients allergic to any of the components of this medication, those with type 1 diabetes, lactic acidosis, diabetic ketoacidosis, severe renal impairment, liver dysfunction, acute alcohol intoxication, pregnant women, and others should not take this medication. Furthermore, this medication should be avoided in cases of sudden deterioration in physical condition or severe heart and lung function decline. This medication can cause hypoglycemia, so care should be taken when used together with other hypoglycemic agents such as insulin or sulfonylureas, and dosages of other medications may need to be adjusted as necessary. Due to the risk of lactic acidosis, any suspicion of dehydration, infection, or renal impairment should be discussed with a physician immediately, and the use of this medication may be temporarily halted. As renal function is critical, regular renal function testing should be conducted before starting this medication and during treatment, and the medication should be discontinued if renal function declines. Special caution is also required for those with heart disease or those undergoing iodine contrast radiography. This medication may need to be discontinued for a certain period before and after surgery or radiological examinations. During treatment with this medication, rare side effects such as acute pancreatitis or bullous pemphigoid may occur, so report any severe abdominal pain or skin abnormalities to a doctor immediately. Prolonged use may lead to vitamin B12 deficiency, so vitamin B12 levels should be checked if symptoms such as anemia or neurological issues arise. This medication can interact with other medications, so it is crucial to inform your doctor or pharmacist if you are taking any other medications. It is advisable to avoid the use of this medication during pregnancy or breastfeeding, and women who plan to become pregnant should also avoid taking this medication. This medication is not recommended for children under the age of 10 or adolescents aged 10 to 17, as its safety and efficacy have not been sufficiently established for this group. Elderly patients may have impaired renal function; hence, renal function should be checked before starting this medication and should be monitored regularly. In case of overdose, lactic acidosis may occur, requiring immediate medical treatment, and in some cases, the medication may need to be removed through hemodialysis. This medication should be kept out of reach of children and should be stored in a sealed container, avoiding moisture and not transferring to another container.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, chest tightness, difficulty breathing, abnormal liver function (abnormal liver function tests, hepatitis), acute myocardial infarction, acute kidney injury, acute cholangitis, acute cholecystitis, cholangitis, angina, unstable angina, cardiac arrest, heart function decline, severe edema, severe allergic reactions, severe skin reactions, respiratory problems, jaundice, severe neurological symptoms, urinary output reduction

Mild side effects

• Pharyngitis
• hypersensitivity
• vitamin B12 reduction and deficiency
• dysgeusia
• cough
• decreased appetite
• diarrhea
• constipation
• nausea
• vomiting

This medication is sensitive to air and moisture, so it should be stored in a sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. This will help preserve the efficacy and safety of the medication for a longer period.

Appearance

Bright yellow, oval-shaped, biconvex film-coated tablet

Package unit

60 tablets/box [(10 tablets/PTP packaging x 6)]