Megatelmic Tablets 40/12.5 Milligrams

Adult dose

For patients whose blood pressure is not adequately controlled with telmisartan alone, this medication should be taken once daily with a beverage, regardless of meals. The dosage is divided into combinations of telmisartan/hydrochlorothiazide 40/12.5mg, 80/12.5mg, 80/25mg, and appropriate dosage should be selected based on the patient's blood pressure control status. No dosage adjustment is necessary for patients with mild to moderate renal impairment, but patients with severe renal impairment (creatinine clearance <30mL/min) should not be treated with this medication.

Child dose

The safety and efficacy of this medication have not been established in children under 18 years of age.

This medication can pose serious risks to the fetus and newborn if used during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. This medication should not be used in individuals with allergic reactions to specific components, in pregnant or breastfeeding women, or in patients with severe liver or kidney disease. Elderly patients or those with elevated potassium levels, liver disease, heart disease, gastrointestinal disease, or renal vascular issues should use this medication cautiously. The hydrochlorothiazide component may cause photosensitivity, so caution is needed when exposed to sunlight, and the risk of skin cancer may increase; therefore, it is important to regularly check skin condition. This medication can cause various side effects, including hypotension, dizziness, headaches, gastrointestinal disturbances, skin rashes, and myalgia, so if symptoms worsen or if unusual reactions are suspected, consult a physician immediately. This medication may interact with other antihypertensive drugs, diuretics, lithium, potassium supplements, etc., so inform your doctor or pharmacist of any other medications you are taking. If planning to become pregnant or during pregnancy, it is recommended to switch to other antihypertensive medications that have established safety. During breastfeeding, this medication may be excreted in breast milk, so it should be avoided and consult your physician if necessary. In case of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration may occur, so visit a healthcare facility immediately for appropriate treatment. This medication is not recommended for children under 18 years of age as safety and efficacy have not been established, and in elderly patients, blood pressure reduction should be carefully monitored to avoid excessive hypotension. Store this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, angioedema (including fatal outcomes), severe skin reactions (severe rash with fever, blisters, skin peeling, pain in mouth/eye mucous membranes), dyspnea, pulmonary edema, acute respiratory distress syndrome (ARDS), jaundice, acute renal failure, severe edema, severe allergic reactions, severe liver impairment (jaundice), severe neurological symptoms (severe

Mild side effects

• Dizziness
• diarrhea
• cough
• pharyngitis
• sinusitis
• hyperuricemia
• hyponatremia
• anxiety
• depression
• insomnia

This medication may be sensitive to air and moisture; hence, it should be stored in a tightly sealed container. A storage temperature between 1 and 30 degrees Celsius at room temperature is recommended to maintain the effectiveness of the medication.

Appearance

White or off-white rectangular tablet

Package unit

30 tablets/bottle