Megapudin Tablet 10mg (Lafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily at bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10 mg of lafutidine per dose orally twice daily.

This medication should not be used in patients who are allergic to any component of this product. This medication contains lactose, so it should not be taken by patients with a genetic condition that prevents lactose digestion. Patients who have had a hypersensitivity to medications, those with compromised liver or kidney function, patients undergoing dialysis, and the elderly should use this medication with particular caution. This medication can rarely cause severe allergic reactions; if symptoms such as paleness, low blood pressure, or difficulty breathing develop, usage should be stopped immediately and medical attention sought. Liver function may deteriorate or jaundice symptoms may appear, so liver health should be monitored regularly, and if abnormalities are found, medication should be stopped and treatment initiated. There can be a decrease in the number of white blood cells or platelets in the blood; if symptoms such as sore throat, fatigue, or fever occur, consult a physician immediately. Rarely, severe side effects such as skin rash, convulsions, or cardiac rhythm disturbances have been reported, so caution is warranted. Common side effects may include constipation, diarrhea, headache, insomnia, dizziness, abdominal pain, and loss of appetite. Gastrointestinal symptoms may especially occur in patients with gastric ulcers or gastroesophageal reflux disease, so monitoring is essential. While taking this medication, there is a potential for concealed malignancies, so if symptoms such as weight loss, recurrent vomiting, or hematemesis occur, testing should be performed. Elderly patients may have diminished physical function, so medication dosages and intervals should be adjusted carefully. Dialysis patients may experience increased drug concentrations in the blood, so should start at a lower dose and proceed cautiously. Pregnant women should only use this medication when the benefit outweighs the risk under a physician's judgment, and nursing women are advised not to take this medication as it may be excreted in breast milk. This medication has not been established as safe for children, so its use is not recommended. This medication should be kept out of reach of children and stored in its original container to maintain the quality and safety of the drug.

• Shock
• anaphylactic symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is advisable to maintain storage temperatures between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle