Medication info

Iryma Tablet (Limaprost Alpha-Dex)

Prescription medicationTabletExpired
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
IntroBio Pharma Co., Ltd.
Appearance
White round tablet
Packaging
Alu-Alu - 84 tablets/Alu-Alu [(21 tablets/Alu-Alu X 4)]
Approval status
Expired

MFDS item code 202001500 · Approved 2020.03.03

This product's status changed to Expired on 2025.03.03. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of symptoms and walking ability in acquired lumbar spinal stenosis; improvement of ischemic symptoms in Buerger's disease
Who uses it
Adults
Adult dosage
1. For improvement of ischemic symptoms such as ulcers, pain, and coldness caused by thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability caused by acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
IntroBio Pharma Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in acquired lumbar spinal stenosis; improvement of ischemic symptoms in Buerger's disease

  • Ulcers
  • pain
  • coldness
  • leg pain
  • leg numbness
View approved original text

It alleviates ischemic symptoms such as ulcers, pain, and coldness caused by obstructive thromboangiitis. Additionally, it reduces subjective symptoms such as leg pain, numbness, and decreased walking ability in patients with acquired lumbar spinal stenosis, thereby relieving discomfort in daily life. This medication helps improve blood circulation and nervous symptoms, enhancing the quality of life for patients.

Dosage and Administration

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness caused by thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability caused by acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication should not be used by women who are pregnant or may become pregnant. This medication contains lactose; patients with a hereditary issue that prevents them from properly digesting lactose should not use it. It should be used cautiously in patients with a tendency to bleed or those taking antiplatelet agents, thrombolytics, or anticoagulants. Using this medication may cause hypersensitivity symptoms such as skin rashes or itching; if these symptoms occur, discontinue use immediately. Occasionally, bleeding may occur, so if bleeding symptoms appear, stop using the drug immediately and consult a physician. This medication may affect the digestive system, presenting symptoms such as diarrhea, nausea, abdominal pain, appetite loss, and heartburn. Liver function abnormalities may cause liver enzyme levels to rise, so caution is needed in patients with liver health issues. Patients may experience increased heart rate or, rarely, bluish discoloration of extremities or low blood pressure; if these symptoms occur, they should inform their physician. Various side effects such as headaches, facial flushing, dizziness, warmth, trembling of the body may appear, so symptoms should be carefully monitored. Patients with lumbar spinal stenosis should closely observe changes in symptoms and decide whether to continue using the medication. Safety during pregnancy has not been established, and uterine contractions have been reported in animal testing, so pregnant women should not use it. Safety has not been confirmed in children, so it is advisable not to use it in pediatric patients. Elderly patients may have reduced bodily functions, so caution in dosage adjustment is necessary. Generally, healthy adults may experience a temporary drop in blood pressure with excessive use, so caution is required.

Side effects

  • Rash
  • itching
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • heat sensation
  • general malaise
  • edema
  • swelling of mammary glands
  • tremors
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius. This helps in maintaining the drug's effectiveness and preventing degradation.

Appearance and packaging

Appearance

White round tablet

Package unit

Alu-Alu - 84 tablets/Alu-Alu [(21 tablets/Alu-Alu X 4)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.