Rezona Tablet 1 mg (Prucalopride Succinate)

Adult dose

This medication is taken orally and can be administered at any time of the day regardless of meals. Adults should take 2 mg once daily. Elderly patients aged 65 and above should start with a dosage of 1 mg once daily and may increase to 2 mg once daily if needed. For patients with severe renal impairment (GFR < 30 ml/min/1.73 m2), 1 mg should be given once daily, and for patients with mild to moderate renal impairment, no dosage adjustment is necessary.

This medication should not be used in certain patients. For example, individuals who are allergic to the ingredients or additives in this medication, patients with severely impaired kidney function, or those with serious gastrointestinal issues should not take this medication. Patients with severe kidney dysfunction or seriously impaired liver function should take this medication with a reduced dosage and with caution. Additionally, patients with heart disease or other serious conditions need to be cautious. The most common side effects during treatment with this medication include headache and gastrointestinal issues, such as nausea, diarrhea, and abdominal pain. These side effects usually occur at the beginning of treatment and often resolve over time. Severe diarrhea may reduce the effectiveness of oral contraceptives, so it is advisable to use additional contraception methods. While this medication has a low potential for drug interactions, caution should be exercised when taken with certain medications, especially those that may affect heart rhythm. This medication is not recommended for use during pregnancy, and women of childbearing age should use effective contraception while taking it. Nursing mothers should also be cautious when taking this medication. This medication is not recommended for children or adolescents under 18 years of age. In cases of overdose, symptoms such as headache, nausea, and diarrhea may occur, and appropriate treatment based on the symptoms will be necessary. During treatment with this medication, dizziness or fatigue may occur, so caution is needed when driving or operating machinery. Finally, this medication should be kept out of reach of children, stored in its original container, and kept away from moisture.

Serious side effects

Chest discomfort

Mild side effects

• Headache
• dizziness
• tremors
• migraine
• palpitations
• vertigo
• nausea
• diarrhea
• abdominal pain
• vomiting

This medication should be stored in a container that does not allow light or air to enter and should be kept away from humid areas. Additionally, it is advisable to store the medication at room temperature between 1°C and 30°C.

Appearance

White round film-coated tablet

Package unit

28 tablets/box [7 tablets/PTP packaging (Alu-Alu) × 4]