Megadias Capsule 50 mg (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses daily after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in patients with inflammatory bowel disease or bowel obstruction syndrome. It is also advisable not to administer this medication in cases of unexplained abdominal pain. Patients with allergies to this medication, its components, or similar classes of drugs should avoid it. Patients with liver disease or a history of liver disease should not use this medication. Children under the age of 15 should not take this medication. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Patients with a history of small intestine or colon disease should use this medication cautiously and may need to avoid it if necessary. Pregnant or breastfeeding women are advised not to take this medication. Seniors over the age of 65 should reduce the dosage of this medication and be closely monitored. Gastrointestinal symptoms such as diarrhea, abdominal pain, and gastrointestinal disturbances may occur when taking this medication, so caution is advised. If diarrhea worsens, dehydration or electrolyte imbalance may occur, and if symptoms appear, discontinue use immediately and consult a doctor. Skin symptoms such as itching, rash, or eczema may commonly occur, so notify a doctor of any abnormal symptoms. There may be liver function abnormalities, so it is important to regularly check liver enzyme levels. Long-term use of this medication should strictly follow the doctor's instructions, and one must not arbitrarily discontinue or increase the dosage. If taken with antacids or drugs containing calcium, magnesium, or aluminum, the absorption may be hindered, so it is advised to take them at least 2 hours apart. Taking this medication with diuretics may enhance diuretic effects, increasing the risk of dehydration and hypokalemia, so caution is needed. When used in combination with cardiac glycosides, the risk of arrhythmias may increase, so it is essential to consult a doctor. If pregnant or breastfeeding, it is advisable not to take this medication as it may affect the fetus or newborn. In case of overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte replenishment is necessary.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, serum elevation of liver enzymes

This medication should be stored in a tightly closed container to protect it from air and humidity. Additionally, it is best to store it at room temperature, between 1 degree and 30 degrees Celsius, avoiding extreme cold or heat.

Appearance

Hard capsule filled with brownish-yellow content, (upper) white, (lower) yellow

Package unit

30 capsules/bottle, 500 capsules/bottle