Linaglipton Duyou Tablet 2.5/500 milligrams

Adult dose

This medication is administered twice daily with meals. 1. For patients not currently treated with Metformin: Take this drug 2.5/500 mg twice a day, 1 tablet at a time, and it can be increased to 2.5/1000 mg, 1 tablet twice daily. 2. In switching from a combination therapy with Linagliptin and Metformin: Patients switching from the existing Linagliptin and Metformin should take the same dosage as their previous regimen.

This medication has the potential for serious side effects such as lactic acidosis, so caution is required. Lactic acidosis is a rare but life-threatening condition, and patients with impaired kidney or liver function, severe infection, dehydration, or heart disease should not use this medication. Additionally, it should not be administered to those with allergies to any of its components, nor in cases of type 1 diabetes, diabetic ketoacidosis, or acute alcohol intoxication. It is advisable for pregnant or breastfeeding women to avoid using this medication. This medication carries a risk of hypoglycemia; therefore, it is important to closely monitor blood glucose levels when taking it in combination with hypoglycemic agents such as insulin or sulfonylureas, and dosage adjustments may be necessary. Elderly patients with reduced kidney function or situations where renal function changes are expected should undergo regular kidney function tests, and treatment should be adjusted or discontinued as necessary. When iodine contrast agents are used for radiographic examinations, this medication should be discontinued before and after the examination, and kidney function should be assessed. Moreover, this medication should be discontinued for a certain period before and after surgery. Possible side effects include gastrointestinal disturbances, abdominal pain, diarrhea, vomiting, and, in rare cases, pancreatitis, skin rashes, and severe joint pain. If these symptoms occur, immediate consultation with healthcare professionals is required. Vitamin B12 deficiency may occur, so it is advisable to regularly check vitamin B12 levels when using this medication for an extended period. This medication may interact with other drugs, so if you are taking any other medications, it is important to inform your healthcare provider, especially if using drugs that may affect kidney function. Lastly, this medication is not recommended for children under 10 years of age, and its effects on driving or operating machinery are not known, so caution should be exercised.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweats
• paleness
• severe rash with fever
• blisters
• skin peeling
• pain in mucous membranes of mouth/eyes

Mild side effects

• Nasopharyngitis
• hypersensitivity
• decreased and deficient vitamin B12
• hypoglycemia
• taste disturbances
• cough
• decreased appetite
• diarrhea
• constipation
• nausea

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. Furthermore, it is important to store it at room temperature between 1°C and 30°C to maintain the drug's efficacy.

Appearance

Bright yellow, double convex, oval film-coated tablets

Package unit

60 tablets / PTP [10 tablets / PTP packaging X 6]