Rinagen Duo Tablets 2.5/1000 mg

Adult dose

This medication is administered twice daily with meals. To reduce gastrointestinal side effects related to metformin use, the dosage increase should be gradual. 1. If currently not treated with metformin: This drug 2.5/500 mg is taken as 1 tablet twice daily, and can be increased to 1 tablet twice daily with 2.5/1000 mg. 2. If difficulty in achieving adequate blood glucose control with monotherapy of metformin,

This medication can cause serious side effects such as lactic acidosis and requires careful monitoring. Lactic acidosis is a condition where there is an excessive accumulation of lactate in the blood, which can be harmful and requires prompt treatment. This drug should not be administered to patients with certain conditions or impaired kidney function. For example, patients with type 1 diabetes, severe kidney impairment, liver dysfunction, serious infections, or dehydration should not take this medication. It is also recommended that pregnant or breastfeeding women avoid using this medicine. This medication can cause hypoglycemia, so blood sugar levels should be monitored closely, especially when taken with other hypoglycemic agents. Kidney function is related to the excretion of this medicine, so regular kidney function tests should be conducted, and administration may need to be discontinued if kidney function declines. Patients with heart disease or a recent history of myocardial infarction should also use this drug with caution. During treatment, rare side effects such as acute pancreatitis or blistering dermatosis may occur, so patients should consult a physician immediately if related symptoms appear. Routine blood tests are necessary to monitor vitamin B12 levels, as prolonged use may lead to a decrease. Furthermore, this medication can interact with other drugs, so it is essential to inform a physician or pharmacist of any concurrent medications. If planning for pregnancy or already pregnant, alternative treatments should be considered, and avoidance during breastfeeding is recommended. It is not recommended for children under ten years of age or adolescents between the ages of ten and seventeen, as safety and efficacy have not been established. Elderly patients are at higher risk for renal impairment, so dosage adjustments and regular monitoring are necessary. In the event of overdose, the risk of lactic acidosis increases, necessitating immediate medical treatment and possibly blood dialysis. This medication should be kept out of reach of children, stored away from moisture, and not transferred to other containers.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, blistering dermatitis, liver abnormalities (abnormal liver function tests, hepatitis), severe allergic reactions (urticaria, angioedema), respiratory issues (dyspnea, asthma, pulmonary dysfunction), angina, acute myocardial infarction, unstable angina, cardiac arrest, liver abnormalities (jaundice), severe neurological symptoms (headache, seizures, consciousness confusion), renal abnormalities (acute kidney injury, end-stage renal disease), angioedema, severe

Mild side effects

• Postnasal drip
• hypersensitivity
• vitamin B12 reduction and deficiency
• taste disorders
• cough
• decreased appetite
• diarrhea
• constipation
• nausea
• vomiting

This medication is sensitive to air and moisture and should be stored in a tightly closed container. It is advisable to keep it at room temperature between 1°C and 30°C to maintain its efficacy for a longer duration.

Appearance

Bright pink, biconvex, oval, film-coated tablet

Package unit

60 tablets/PTP [10 tablets/PTP packaging x 6]