EZPru Tablet 2 mg (Prucalopride Succinate)

Adult dose

This medication is taken orally and can be administered at any time of day regardless of meals. Adults should take 2 mg once daily. For elderly individuals aged 65 and over, the initial dose is 1 mg once daily, which can be increased to 2 mg once daily if needed. Patients with severe renal impairment and severe hepatic impairment should take 1 mg once daily. For patients with mild to moderate renal impairment and mild to moderate hepatic impairment, dose adjustments are not necessary.

This medication should not be used in certain patients. For example, individuals allergic to the active ingredient or any excipients should avoid taking this medication. Additionally, patients with severely impaired renal function requiring dialysis or those with serious gastrointestinal issues could be at risk when using this medication. This medication contains lactose and should not be administered to patients with genetic issues such as lactose intolerance. For patients with severe renal impairment, the dosage should be reduced and used with caution. Patients with other serious conditions such as liver or heart diseases also need to be monitored, especially those with a history of arrhythmias or ischemic heart disease. Dosage adjustment is also necessary for patients with severely impaired liver function. This medication can commonly cause gastrointestinal symptoms such as headache, abdominal pain, nausea, and diarrhea. These symptoms usually appear early in treatment and often resolve naturally over time. Rarely, symptoms like palpitations, dizziness, and fatigue may occur; if these symptoms worsen, consult a doctor. Severe diarrhea during the use of this medication may reduce the effectiveness of oral contraceptives, so it is advisable to use additional contraceptive methods. The likelihood of interactions with other medications is low, but caution should be exercised when taking medications that can prolong the QT interval. Additionally, some medications may alter blood concentration levels, making it essential to consult a healthcare provider or pharmacist. Use of this medication is not recommended for pregnant women, and women of childbearing age should use effective contraception while taking this medication. Breastfeeding women are also advised against using this medication, and it should not be administered to children or adolescents. In cases of overdose, symptoms like headache, nausea, and diarrhea may appear, requiring appropriate treatment based on the symptoms. Caution is advised when driving or operating machinery due to potential dizziness or fatigue.

Serious side effects

Chest discomfort (possible severe allergic reaction), facial swelling (possible severe allergic reaction), peripheral edema, swelling (possible severe edema), ventricular extrasystoles (cardiac disorder), spinal stenosis (may be serious), diabetic neuropathy, facial paralysis (possible serious neurological symptoms)

Mild side effects

Headache, gastrointestinal symptoms (abdominal pain, nausea, diarrhea), dizziness, tremors, palpitations, vomiting, dyspepsia, rectal bleeding, bloating, abnormal bowel sounds, increased urinary frequency, fatigue, fever, malaise, abdominal distension, abdominal discomfort, gastroesophageal reflux disease, rectal pain, hemorrhoids, functional dyspepsia, loose stools, esophagitis, duodenal ulcer, nasopharyngitis, bronchitis, shingles, tinea, bacterial vaginosis, bacterial bronchitis, facial swelling, and

This medication should be stored in a container that protects against light and air, avoiding exposure to moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu*2)