Donepezil Tablet 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

For donepezil hydrochloride, administer 5 mg once daily before bedtime. Maintain the dose at 5 mg for 4 to 6 weeks, and after evaluating the clinical response during this period, the dose may be increased to 10 mg. When increasing to 10 mg per day, administer while monitoring for gastrointestinal adverse reactions. Women aged 85 years or older who are underweight should not exceed 5 mg per day, and caution is advised due to the potential for adverse reactions.

Child dose

There is no experience with use in children.

This medicine should not be used by patients who are allergic to specific ingredients or by women who are pregnant or breastfeeding. Also, it should not be administered to patients with lactose intolerance or certain genetic digestive disorders. Patients with heart disease or cardiac conduction disorders should use this medicine cautiously, as bradycardia or arrhythmia may occur. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be careful, as there is a possibility of gastrointestinal bleeding or ulcer exacerbation. Patients with asthma or obstructive pulmonary disease should be cautious, as bronchoconstriction may worsen when using this medicine. Patients with extrapyramidal disorders like Parkinson's disease should also use it cautiously as symptoms may worsen. Serious side effects such as fainting, heart problems, gastrointestinal bleeding, liver dysfunction, seizures, muscle abnormalities, or respiratory difficulties may occur while taking this medicine; if any abnormal symptoms arise, consult a doctor immediately. Additionally, common side effects such as nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, tremors, anxiety, drowsiness, fever, rash, itching, myalgia, urinary incontinence, hypertension, palpitations, bradycardia, atrial fibrillation, high blood pressure, low blood pressure, abdominal pain, thrombocytopenia, leukopenia, anemia, neuroexcitation, confusion, involuntary movements, gait disturbances, aggressive behavior, confusion, hallucinations, drowsiness, pain, hives, lethargy, insomnia, and vascular abnormalities may occur. This medicine can affect the heart, so patients with heart disease or electrolyte imbalances may need an electrocardiogram. Be cautious while driving or operating machinery as dizziness or drowsiness may occur. Women who are pregnant or breastfeeding should avoid using this medicine, and if necessary, should consult a specialist before deciding. Safety in children has not been established, so it is advisable not to use it in children. This medicine may interact with other medications, so inform your healthcare provider about any other medications you are taking. Overdose may lead to risks such as nausea, vomiting, bradycardia, hypotension, and respiratory depression, so it is essential to adhere to the prescribed dosage and administration instructions. Keep out of the reach of children and do not transfer to other containers for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in the mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues with cough + fever, yellowing of the skin or eyes (jaundice), feeling very lethargic, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

• Nausea
• vomiting
• loss of appetite
• diarrhea
• headache
• fatigue
• dizziness
• insomnia
• tremors
• anxiety

This medicine should be stored in a tightly closed container to prevent air or moisture from entering. It is recommended to keep it at room temperature between 1 to 30 degrees.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets per bottle