Lerogen (Levocetirizine Hydrochloride)

Adult dose

Adults and children over 6 years: Administer 1 tablet (Levocetirizine Hydrochloride 5mg) once daily orally, regardless of meals. Adjust dosage according to kidney function. - Normal kidney function (eGFR ≥ 90): 1 tablet once a day - Mild renal impairment (eGFR 60 -< 90): 1 tablet once a day - Moderate renal impairment (eGFR 30 -< 60): 1 tablet every other day

Child dose

Children over 6 years: Administer 1 tablet (Levocetirizine Hydrochloride 5mg) once daily orally, regardless of meals. Adjust dosing appropriately based on age and symptoms.

This medication should not be used by patients with allergies to specific components or those hypersensitive to hydroxyzine or piperazine derivatives. Patients with end-stage renal disease or those undergoing dialysis should not be administered this medication. It should not be used in infants under 1 year of age, and children under 6 years should be given the liquid form instead of the tablet form. This tablet contains lactose; therefore, patients with lactose intolerance or specific genetic lactose metabolism disorders should avoid taking it. Patients with impaired kidney or liver function, as well as the elderly, should use this medication with caution as blood concentrations may increase. Side effects related to the nervous system such as drowsiness, headache, and dizziness may occur when taking this medication, as well as hypersensitivity reactions like gastrointestinal symptoms or skin rashes. Care is necessary for activities requiring concentration such as driving or operating machinery after taking this medication, and it should be avoided in combination with alcohol or central nervous system depressants. Patients at risk of urinary retention or those with epilepsy need special attention when using this medication. Pregnant or breastfeeding women must consult a doctor before using this medication, as the effects on the fetus or newborn have not been fully elucidated. Dosage adjustments are required for children and the elderly, particularly reducing the dose for the elderly due to decreased kidney function. If undergoing allergy testing, it is advisable to discontinue this medication 3-5 days prior to testing. In cases of overdose, symptoms such as drowsiness or agitation may occur, and there is no specific antidote; treatment should be symptomatic, and blood dialysis is ineffective in eliminating this medication.

Serious side effects

• Urticaria
• swelling
• angioedema
• anaphylactic shock
• respiratory distress
• hives
• hypertension
• stress fractures
• pneumonia
• hives

Mild side effects

• Drowsiness
• fatigue
• headache
• numbness
• agitation
• lethargy
• tiredness
• dizziness
• heaviness of the head
• excitement

This medication should be stored in a tightly sealed container protected from light. Additionally, it is important to maintain storage at a temperature between 1 to 30 degrees Celsius to preserve the medication's efficacy.

Appearance

White or pale yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle