Kerafutin Tablet 10 mg (Rabeprazole)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dosage is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks; however, healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dosage is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks; however, healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dosage is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks; however, healing time may occasionally vary among patients. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dosage is 10mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This medication should not be used in patients with hypersensitivity to its components. In addition, this medication contains lactose, so it should not be administered to patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Caution should be exercised when administering this medication to patients with a history of drug hypersensitivity, liver or kidney dysfunction, those undergoing dialysis, and elderly patients. During the administration of this medication, serious allergic reactions such as anaphylaxis may occur, so symptoms should be carefully monitored. Symptoms of liver dysfunction or jaundice may develop, so regular liver function tests should be conducted, and administration should be stopped immediately if abnormalities are detected. Blood abnormalities such as agranulocytosis or thrombocytopenia may occur, so if symptoms such as sore throat, fever, or generalized fatigue appear, immediate consultation with healthcare personnel is necessary. Rarely, serious side effects such as seizures, skin rashes, or heart blocks have been reported, so if any abnormal symptoms occur, administration should be stopped immediately and appropriate treatment should be sought. Various side effects can occur in different systems such as the gastrointestinal, central nervous, and cardiovascular systems, so changes in symptoms should be carefully monitored during administration. Especially if a malignancy is suspected, diagnosis may be delayed due to this medication, so if suspicious symptoms arise, testing must be conducted. Elderly patients may have decreased physical function, so dosage and intervals should be adjusted and taken cautiously. Patients undergoing dialysis may experience elevated blood concentrations, so administration should start at a low dose and be conducted with caution. Pregnant women or women who may become pregnant should only take this medication if the benefits outweigh the risks as determined by a doctor, and breastfeeding women are advised not to take this medication. Safety in pediatric patients has not been established, so it is advisable not to administer this medication to children. This medication must be stored out of reach of children, and transferring the medication from its original container to another can pose risks of misuse or quality deterioration, so it should be stored in the original container.

• Shock
• anaphylaxis symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1°C and 30°C.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle