Esome 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Additional 4 weeks if esophagitis is untreated - Maintenance therapy for prevention of recurrence: 20 mg once daily - Treatment of symptoms without esophagitis: 20 mg once daily - As needed, 1 dose per day

Children's dosage

Adolescents aged 12 and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Treatment of symptoms without esophagitis: 20 mg once daily - Continuous symptoms after symptom relief

This medication should not be administered to certain patients. For instance, individuals with an allergy or previous hypersensitivity reaction to this medication or its components, as well as certain antibiotics or medications used in Helicobacter pylori eradication therapy, should not take this product. It is also not recommended for breastfeeding women and those with a history of myocardial infarction. This medication can cause various side effects, commonly headaches, abdominal pain, diarrhea, and nausea. Rarely, serious side effects such as blood abnormalities, hypersensitivity reactions, mental symptoms, liver function abnormalities, and skin rashes have been reported. Regular monitoring is necessary for electrolyte imbalances such as hypomagnesemia, especially with long-term use. This drug may interact with other medications; therefore, it is essential to discuss concurrent medications with a physician or pharmacist. Care is needed when used with medications affecting blood coagulation, antiviral agents, antibiotics, antiepileptics, etc., and when starting or stopping this medication, blood concentration or effects must be closely observed. Data on the safety of this medication during pregnancy is limited; thus, it should be administered with caution to pregnant women, and it is recommended not to take this medication while breastfeeding. In case of overdose, no specific antidote is available; thus, treatment and general management based on symptoms are required. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to maintain quality.

Serious side effects

Hives, angioedema, anaphylaxis reaction/shock, severe hypomagnesemia, mental confusion, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, pancreatitis, increased liver enzymes, hepatitis with or without jaundice, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia with systemic symptoms

Mild side effects

• Headache
• dizziness
• sensory disturbances
• drowsiness
• taste disorders
• blurred vision
• vertigo
• bronchospasm
• abdominal pain
• constipation

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture and should be kept at a temperature between 1°C and 30°C.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box [28 tablets (14 tablets/PTP x 2)], 30 tablets/bottle, 300 tablets/bottle