Megarosartan CL Tablet

Adult dose

The standard adult dosage is 1 tablet of Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily. Doses exceeding Losartan Potassium 100 mg/Hydrochlorothiazide 25 mg per day are not recommended. 1. Begin with Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily, and if blood pressure is still not controlled after 3 weeks of treatment, the maximum dose of Losartan Potassium.

Child dose

Not to be administered to children and adolescents (under 18 years of age).

This medication can cause severe harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Additionally, patients with allergies to this medication or its components, severely impaired kidney function, or certain electrolyte imbalances should not take this medication. Patients with excessively low blood pressure, impaired kidney or liver function, hyperuricemia or gout, elderly patients, etc., should use this medication with caution and have regular blood tests and physical condition checks. The hydrochlorothiazide component can cause electrolyte imbalances, so sodium and potassium levels should be frequently monitored, and if symptoms such as dehydration, muscle cramps, or fatigue occur, a doctor should be consulted immediately. During the use of this medication, potassium supplements or salt substitutes containing potassium should not be taken without consulting a physician, and caution is also needed when used in combination with other antihypertensive medications or diuretics. Moreover, this medication may react sensitively to sunlight, so UV protection should be taken when going outside, and any skin abnormalities should be reported to healthcare providers immediately. Caution should be exercised while driving or operating machinery, particularly at the initiation of treatment or when changing doses as dizziness or drowsiness may occur. For long-term use of this medication, it is important to regularly check for abnormalities through blood tests and evaluation of kidney and liver functions.

Serious side effects

Hives, angioedema (swelling of the lips and eyelids and facial rash), desquamation of the skin of the palms, hemolysis, facial swelling, angioedema (laryngeal/glottic edema that may cause airway obstruction, edema of the face/lips/pharynx/tongue), mucosal membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), necrotizing vasculitis, acute respiratory distress syndrome (ARDS), jaundice, hepatitis, renal failure, hemolytic anemia, regeneration.

Mild side effects

Abdominal pain, swelling/edema, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory tract infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial swelling, fever, orthostatic hypotension, syncope, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, anorexia, constipation, dental pain, dry mouth, dyspepsia, flatulence, gastritis, vomiting.

This medication is sensitive to light, so it should be stored in an opaque container to prevent light exposure. Additionally, it is best to store the medication at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle