Megacoxib Capsule 100mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken without regard to meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg given on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication can cause gastrointestinal bleeding in individuals who regularly consume more than three glasses of soju per day, so it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular thrombotic events such as myocardial infarction and stroke, so it should be used at the lowest effective dosage for the shortest duration possible, and cardiovascular symptoms should be reported to healthcare professionals immediately. Serious gastrointestinal adverse reactions such as perforation, ulceration, or bleeding may occur, so if symptoms like epigastric pain, dyspepsia, tarry stools, or hematemesis appear, one should go to the hospital immediately. This medication should not be taken by individuals with a known allergy to it or who have had hypersensitivity reactions to sulfonamides, aspirin, or other non-steroidal anti-inflammatory drugs. Patients with severely impaired liver or kidney function, active peptic ulcers or gastrointestinal bleeding, heart failure, as well as pregnant or lactating women should not use this medication. Patients with mild liver or kidney dysfunction or diseases such as asthma, hypertension, diabetes, and edema should take this medication with caution and regularly check their health status as directed by a physician. During treatment with this medication, side effects such as headache, dizziness, dyspepsia, vomiting, diarrhea, skin rash, swelling, hypertension, cough, and others may occur. If unusual symptoms persist or worsen, please consult a healthcare professional. In particular, if severe allergic symptoms such as skin rashes, blisters, itching, or fever occur, immediately discontinue the medication and visit a hospital. This medication is metabolized in the liver, which can alter blood concentration when taken with certain other medications; hence, notify your doctor if you are on other medications, as dosage adjustments may be necessary. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately, and a physician should be consulted. This medication can also be excreted in breast milk, so nursing mothers should avoid taking it or consider stopping breastfeeding. The elderly may be at increased risk for reduced kidney, liver, or heart function, requiring additional caution with this medication, including possible dosage adjustments and regular health status monitoring. Patients taking this medication long-term should have regular blood tests and liver and kidney function tests, and treatment may need to be stopped if any abnormal findings arise. Overdose may lead to lethargy, drowsiness, nausea, vomiting, and abdominal pain, and in severe cases, renal failure or respiratory depression may occur, necessitating immediate emergency care. This medication should be kept out of the reach of children, and care should be taken not to transfer it to other containers, as this may alter its quality.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased NAG, positive urinary hematuria, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, headache, leg cramps, tension, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal behavior, loss of smell, loss of taste, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, hallucinations, anaphylactic reactions, hearing loss, ear disorders, otalgia, hearing impairment, cholelithiasis, jaundice, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pyoderma, contact dermatitis, injection site reactions, skin nodules, chest pain, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, herpes zoster, pneumonia, respiratory distress, elevated ALT, hearing impairment

This medication should be stored in a tightly sealed container to prevent air from entering. It is best kept in a cool place between 15 and 30 degrees Celsius. Proper storage can help maintain the drug's efficacy over time.

Appearance

A white or light yellow powder filled in white capsules with blue stripes on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle