Medication info
Candesartan and Amlodipine Tablets 16/5 milligrams

Candesartan and Amlodipine Tablets 16/5 milligrams

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.94mg / 1 tabletCandesartan Cilexetil›16mg / 1 tablet
Manufacturer / importer
(주)녹십자
Appearance
Light yellow round tablets
Packaging
Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle
Approval status
Active

MFDS item code 202000968 · Approved 2020.02.14 · Insurance code 643605800

Summary

Main use
Improvement in blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dose for adults is 1 tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time daily (e.g., in the morning). In patients with renal impairment, a starting dose of 4 milligrams of Candesartan Cilexetil is recommended, so administering this medication as initial treatment is not advisable. For patients with liver impairment, a starting dose of 2 milligrams of Candesartan Cilexetil is recommended.
Child dose
Safety and efficacy in pediatric patients under 18 years of age have not been established, and administration of this medication is not recommended.

Ingredients

Manufacturer
(주)녹십자

Efficacy & effects

Improvement in blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

Patients with essential hypertension may benefit from the use of this medication when blood pressure is not adequately controlled with monotherapy using Candesartan Cilexetil or Amlodipine. These medications help effectively lower blood pressure, thereby reducing the burden on the heart and blood vessels and decreasing the risk of complications. Thus, this medication is used for appropriate blood pressure management.

How to take

Adult dose

The recommended dose for adults is 1 tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time daily (e.g., in the morning). In patients with renal impairment, a starting dose of 4 milligrams of Candesartan Cilexetil is recommended, so administering this medication as initial treatment is not advisable. For patients with liver impairment, a starting dose of 2 milligrams of Candesartan Cilexetil is recommended.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, and administration of this medication is not recommended.

Precautions

This medication can cause severe damage or death to the fetus and newborn, particularly during pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with specific conditions, such as those with severe liver impairment or those with diabetes and severe renal impairment. Elderly patients or those with high potassium levels, as well as patients with weakened liver or kidney function, should exercise special caution when administering this medication. Side effects such as headache, dizziness, blood pressure changes, digestive discomfort, and skin rash may occur, and if symptoms are severe, consultation with a physician is recommended. Because the blood pressure-lowering effect can be strong, patients with hypotension or poor blood volume should manage their condition well before taking this medication. In patients with heart failure, kidney function and blood potassium levels should be monitored regularly while taking this medication, and dosage adjustments should be made cautiously. This medication may interact with other antihypertensive medications, diuretics, potassium supplements, etc., so all medications being taken should be disclosed to the physician. Pregnant or nursing women are advised against taking this medication; if it is absolutely necessary, it should be taken under the guidance of a healthcare professional. Children under 18 years of age should not use this medication as its safety and efficacy have not been established. Caution is needed when driving or operating machinery due to the potential for dizziness or drowsiness. Overdosing on this medication can lead to severe hypotension and dizziness, so it is crucial to adhere to the prescribed dose and to seek medical attention immediately in case of an overdose. Store out of reach of children and do not transfer to another container; keeping in the original packaging is safer.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema (swelling of the face, lips, tongue, throat, etc.), shock, syncope, loss of consciousness, severe hypotension, acute kidney failure, liver dysfunction, jaundice, hepatitis, intestinal angioedema, dyspnea, severe allergic reactions, severe edema, increased blood pressure, angioedema, toxic epidermal necrolysis, rhabdomyolysis, acute hypotension, shock, altered mental status, vision disturbances, paralysis, seizures due to elevated blood potassium levels, interstitial pneumonia, acute

Mild side effects

  • Headache
  • peripheral edema
  • increased triglycerides
  • flushing
  • dizziness
  • facial nerve paralysis
  • nasopharyngitis
  • bronchitis
  • conjunctivitis
  • upper respiratory infection
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  • pneumonia
  • dental pain
  • abdominal discomfort
  • abdominal pain
  • upper abdominal pain
  • gastroesophageal reflux disease
  • abdominal mass
  • diverticulosis
  • gastric polyp
  • erosive gastritis
  • increased creatinine levels
  • increased urea levels
  • increased liver enzymes
  • elevated ALT
  • elevated AST
  • chest pain
  • chest discomfort
  • muscle weakness
  • flank pain
  • musculoskeletal pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the efficacy and safety of the medication for a longer period.

Appearance and packaging

Appearance

Light yellow round tablets

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.