Clorid (Clopidogrel Hydrogen Sulfate)

Adult dose

○ Adults 1. In patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer clopidogrel 75 mg orally once daily. 2. In patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), begin treatment on the first day with a loading dose of 300 mg of this medicine once daily, followed by a maintenance dose of 75 mg orally once daily. In this case, aspirin 75 ～ 325 mg should be administered concomitantly with this medicine once daily. 3. In patients with atrial fibrillation, administer 75 mg of this medicine orally once daily. In this case, aspirin 75 ～ 100 mg should be administered concomitantly with this medicine once daily. ○ Patients with renal impairment: Treatment experience in patients with renal impairment is limited. ○ Patients with hepatic impairment: Treatment experience in patients with moderate liver disease with a bleeding diathesis is limited. This medicine may be administered with or without food.

This medication is an antiplatelet agent that prevents platelets from aggregating and forming blood clots. Patients with genetically reduced function of a specific enzyme (CYP2C19) may experience reduced effectiveness of this medication, and alternative treatment options may need to be considered. Additionally, concurrent use of this medication with drugs that activate certain enzymes may increase the concentration of the active ingredient of this medication, raising the risk of bleeding, and such combinations should be avoided. This medication should not be administered to patients with hypersensitivity or active bleeding, severe liver damage, nursing mothers, and patients with genetic issues such as lactose intolerance. Patients at high risk of bleeding, liver disease patients, renal impairment patients, those with acute stroke, hypertension patients, elderly patients, and those with low body weight should be treated with caution, and particularly, patients planned for surgery should stop taking this medication 5 to 7 days before surgery. If bleeding symptoms or abnormalities related to blood occur while taking this medication, consult a doctor immediately. Additionally, care must be taken when this medication is taken with other drugs that have a risk of bleeding, as this increases the risk of bleeding. Pregnant or nursing women should consult a doctor before taking this medication, and if nursing, careful consideration of whether to continue the medication is essential. Safety in children has not been established, and elderly individuals may be at higher risk of bleeding due to decreased bodily function, requiring careful dosage adjustment and monitoring. In cases of overdose, bleeding time may prolong, leading to complications, so the specified dosage must be adhered to while taking this medication. Store in a safe place out of reach of children and preferably do not transfer to another container.

Hemorrhage, gastrointestinal bleeding, hospitalization required for bleeding, purpura, contusion, hematoma, epistaxis, hematoma, hematuria, intraocular hemorrhage, intracranial hemorrhage, major bleeding, life-threatening bleeding, fatal bleeding, hemorrhagic stroke, need for transfusion, thrombocytopenia, neutropenia, aplastic anemia, abdominal pain, dyspepsia, diarrhea, nausea, rash, pruritus, headache, dizziness, chest pain, accidental injury, influenza-like illness, pain, fatigue, edema, hypertension, depression, upper respiratory tract infection, dyspnea, rhinitis, bronchitis, cough, urinary tract infection, autonomic nervous system disorders (syncope, palpitations), myasthenia, fever, hernia, heart failure, atrial fibrillation, leg cramps, sensory impairment, neuralgia, sensory anomalies, lightheadedness, constipation, vomiting, increased liver enzymes, gout, hyperuricemia, arthritis, arthropathy, anxiety, insomnia, anemia, hematochezia, hematoma, decreased platelets, pneumonia, sinusitis, eczema, skin ulcer, cystitis, cataract, conjunctivitis, reduced motor function, tremor, speech disorder, abnormal gait, hyperkinesia, ataxia, perceptual disturbances, insomnia, depression, forgetfulness, labyrinthitis, accident anomalies, abnormal behavior, rigidity, facial edema, syncope, hematochezia, thrombocytopenia, vasculitis, hypotension, bronchospasm, interstitial pneumonia, eosinophilic pneumonia, colitis, pancreatitis, gastritis, stomatitis, hepatitis, acute liver failure, herpes zoster, erythematous rash, maculopapular rash, urticaria, itching, angioedema, vesicular dermatitis, drug-induced hypersensitivity syndrome, eosinophilia, drug rash, lichen planus, myalgia, glomerulopathy, gynecomastia, fever, abnormal liver function tests, increased blood creatinine, allergic symptoms, ischemic necrosis, generalized edema, gastritis, hemorrhagic gastroenteritis, duodenal ulcer, gastric ulcer, perforated gastric ulcer, upper gastrointestinal tract ulcer bleeding, distension, hyperbilirubinemia, infectious hepatitis, fatty liver, hemorrhagic arthropathy, hematuria, hemoptysis, retroperitoneal hemorrhage, surgical wound bleeding, ocular hemorrhage, pulmonary hemorrhage, purpura, aplastic anemia, hypochromic anemia, agranulocytosis, granulocytopenia, leukemia, leukopenia, eosinophilia, excessive menstruation, hemothorax, herpes zoster, erythematous rash, maculopapular rash, urticaria, renal function abnormalities, acute kidney failure, anorexia, weight loss, visual disturbances, labyrinthitis, weight gain, facial flushing, thirst, polyuria, arrhythmia, speech disorder, abnormal gait, hyperkinesia, ataxia, hiccups, dysphagia, tongue disorders, abnormal behavior, rigidity, visual field disturbances, dry eyes, transient blindness, congestion, urination disorders, uremia, hypoglycemia, bradycardia, tinnitus, contact dermatitis, gynecomastia, increased PSA, cholecystitis, hematemesis, spinal hematoma

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is advisable to keep the medication at room temperature, ideally between 1 degree and 30 degrees Celsius, without exposing it to extreme heat or cold. Proper storage will help maintain the medication's effectiveness over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle